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  • 1
    Electronic Resource
    Electronic Resource
    Prevention of hepatitis B flare-up during chemotherapy using lamivudine: case report and review of the literature (1999)
    Springer
    Annals of hematology 78 (1999), S. 247-249 
    Details
    ISSN: 1432-0584
    Keywords: Key words Lymphoma ; Chemotherapy ; Hepatitis B reactivation ; Lamivudine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Reactivation of chronic hepatitis B in patients receiving cytotoxic treatment for non-Hodgkin's lymphoma is well documented. We report a case of a patient with chronic hepatitis B who was treated by chemotherapy because of non-Hodgkin's lymphoma. After the second cycle of chemotherapy she developed a severe flare-up of hepatitis B. Liver biopsy revealed highly active hepatitis and confluent necroses. Within 3 weeks, the patient recovered spontaneously. Prophylactic treatment with lamivudine (Epivir,Glaxo-Wellcome, 150 mg b.i.d.) led to a decrease of HBV-DNA below the detection limit. Further chemotherapy was administered and autologous stem cell transplantation was successfully performed without another reactivation of hepatitis B. Antiviral treatment was stopped 16 weeks after stem cell retransfusion. So far, no further flare-up of hepatitis B has occurred and the patient's lymphoma has not relapsed. Thus, the case described here indicates a possible role of lamivudine in preventing hepatitis B flare-up during antineoplastic chemotherapy. We suggest that lamivudine be considered for prophylaxis against fulminant hepatitis in patients with chronic HBV infection undergoing high-dose antineoplastic therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050510
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Computed tomography after lymphangiography in the diagnosis of intestinal lymphangiectasia with protein-losing enteropathy in Noonan's syndrome (2000)
    Springer
    European radiology 10 (2000), S. 1591-1593 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Noonan's syndrome – Intestinal lymphangiectasia – Pulmonary lymphangiectasia – Lymphangiography – CT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Noonan's syndrome is a rare congenital disorder that may be associated with abnormalities in the lymphatic drainage. In this case of a 21-year-old man CT after bipedal lymphangiography confirmed the diagnosis of intestinal lymphangiectasy causing protein-losing enteropathy in Noonan's syndrome by showing contrast-enhanced abnormal lymphatic vessels in the mesentery and the intestinal wall. Because of the benefit of diet in case of intestinal involvement, we recommend a thorough documentation of the lymphatic drainage with lymphangiography followed by CT, if clinical signs of lymphatic dysplasia, such as pleural effusions, lymphedema, or hypoproteinemia are present.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300000384
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Leitsymptom Erbrechen (1998)
    Springer
    Der Internist 39 (1998), S. 1055-1061 
    Details
    ISSN: 1432-1289
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Emesis ) versteht man das retrograde Herausbefördern von Magen-und/oder Dünndarminhalt nach außen. Im allgemeinen gehen Übelkeit (Nausea), Hypersalivation und Würgen als Prodromi dem eigentlichen Brechakt voraus. Häufig wird jedoch durch dieselben Stimuli, die zum Erbrechen führen, nur Übelkeit ausgelöst, ohne daß das Stadium des Erbrechens überhaupt erreicht wird. In einigen Fällen kann umgekehrt auch Erbrechen ohne vorausgehende Übelkeit auftreten. Unter dem Symptom Übelkeit versteht man ein pharyngeales und/oder epigastrisches Krankheitsgefühl, häufig in Verbindung mit vasomotorischen Begleitphänomenen wie Schwitzen und Tachykardie. Funktionell besteht eine antrale Hypomotilität und duodenale Retroperistaltik.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001080050277
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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