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  • 1
    Electronic Resource
    Electronic Resource
    DNA flow cytometry of thymomas (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 15 (1989), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Forty-seven thymomas have been examined by DNA flow cytometry and results correlated with histology, stage, associated clinical features and survival. Twenty-five cases were DNA diploid, 14 were ancuploid and no results could be obtained for eight cases. The presence of ancuploidy correlated with more advanced (stage II and III) disease and the presence of myasthenia gravis and was more frequent in epithelial predominant thymomas. Tumour recurrence was more frequent in DNA aneuploid tumours, stage II/III disease and epithelial predominant neoplasms. Multifactorial analysis showed that DNA aneuploidy was predictive of tumour recurrence independent of the effects of stage and histology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1989.tb03043.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Dermatofibrosarcoma protuberans: a clinicopathological and immunohistochemical study with a review of the literature (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 9 (1985), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Forty-one cases of dermatofibrosarcoma protuberans are presented. The clinical features and histopathological appearances are described. Immunohistochemical staining of thirteen cases with antisera to lysozyme, α1-antichymotrypsin and S-100 protein has provided no evidence to support either a histiocytic or neuroectodermal origin for these tumours. In reviewing the literature, the histogenetic origin, differential diagnosis and malignant potential of dermatofibrosarcoma protuberans are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1985.tb02878.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Is myosin in the cochlea a basis for active motility? (1980)
    [s.l.] : Nature Publishing Group
    Nature 288 (1980), S. 491-492 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Myosin was detected in the hair cells of the guinea pig cochlea by indirect immunofluorescence using an antiserum raised against human smooth muscle myosin4. Immunofluorescence was visible in very specific areas of the organ of Corti. The stereocilia fluoresced strongly along their length (Fig. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/288491a0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Cell kinetics of human gastric mucosa and gastric cancer in organ culture (1991)
    Springer
    Virchows Archiv 418 (1991), S. 457-461 
    Details
    ISSN: 1432-2307
    Keywords: Gastric mucosa ; Gastrointestinal neoplasms ; Cell cycle ; Organ culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cell kinetics of human gastric epithelium in organ culture have been measured using flash labelling with tritiated thymidine and the metaphase arrest technique to estimate cell birth rates. Normal gastric antral and body mucosa have been compared with mucosa showing gastritis and gastric carcinoma. Labelling indices with tritiated thymidine in normal gastric mucosa declined over a 48-h period suggesting that essential growth factors were lacking. Labelling indices and cell birth rates were higher in gastritis than in normal mucosa and highest in gastric carcinoma. Labelling indices were higher in intestinal-type gastric carcinoma than diffuse carcinoma. In metaphase arrest experiments carcinomas showed on average an eightfold increase in resistance to the metaphase-arresting properties of vincristine when compared with normal mucosa. The validity of using the metaphase arrest technique to measure cell birth rate in gastric cancers in view of this vincristine resistance is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01605933
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    Paper (German National Licenses)
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