ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
The release behavior of typical commercial tissue expanders has been examined by carrying out two kinds of experiments: (1) Determination of chemical nature and its modification after in vivo use by X-ray photoelectron spectroscopy for chemical analysis. This study has been parallelled by scanning electron microscopy with associated energy dispersive X-ray analysis of surface, as well as by silicon compounds analysis of tissues around implants. (2) Kinetic examination of silicon compounds released by the biomaterial in physiologic solution at 36 ± 0.3°C. Results of these investigations have shown independently that the starting material was not a filler-free, pure polymer, but a composite, reinforced elastomer, with the reinforcing agent most seemingly represented by silicon dioxide. Release of latter, with a relatively fast kinetics, is compatible with data of the simulating laboratory runs in the physiologic solution. All these facts seem to rule out any hypothesis of a prevailing siloxane oligomer migration. The correlation of kinetic and physicochemical tests with the in vivo behavior is discussed. © 1995 John Wiley & Sons, Inc.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820290109
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