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  • 1
    Electronic Resource
    Electronic Resource
    Development of squamous cell carcinoma in chronic discoid lupus erythematosus (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 3 (1978), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Squamous cell carcinoma was seen in five patients with chronic discoid lupus erythematosus during a review of 120 cases seen originally in the years 1958–1962.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1978.tb01480.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Chronic leg ulcers treated by the pinch graft method (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 97 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Forty-nine patients with chronic leg ulcers were treated by pinch grafting. The initial success of this procedure was high for both gravitational and arterio-sclerotic ulcers. Over half the grafted gravitational ulcers and 70% of grafted arteriosclerotic ulcers were intact after 2 years. Some grafts remained stable for 6 years. Arteritic ulcers did not respond as well; none of the grafted ulcers survived more than 6 months.Pinch grafting is still a simple, cheap and effective therapy offering prolonged graft stability as well as quicker healing to those patients who are not fit for more extensive surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb15185.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Primary amyloidosis and myelomatosis associated with excessive fibrinolytic activity (1976)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 94 (1976), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case of primary amyloidosis is described in association with Bence-Jones myeloma and increased fibrinolytic activity. Epsilon aminocaproic acid reversed the fibrinolytic activity and clinical improvement was maintained with melphalan and prednisolone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1976.tb05148.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Juvenile plantar dermatosis (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 2 (1977), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1977.tb01566.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Prognosis in cutaneous lupus erythematosus (1978)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 98 (1978), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1978.tb13592.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    A comparison of glycoprotein biosynthesis in basal cell carcinoma and normal epidermis (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 11 (1986), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Protein and N-linked glycoprotein biosynthesis in normal epidermis and basal cell carcinomas were measured by the incorporation of 3[H] leucine and 3[H] mannose. Compared with normal epidermis, basal cell carcinomas had a reduced overall protein synthesis accompanied by an increased N-linked glycoprotein synthesis. Polyacrylamide gel electrophoresis showed that in the tumours the glycoprotein synthesis was restricted to molecular weight ranges with peaks at 95K (74K) and 38K, whereas in normal epidermis they were found at 95K, 62K, 52K and 43K.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1986.tb00451.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    The effect of PUVA therapy on glycoprotein biosynthesis in uninvolved psoriatic epidermis (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 16 (1991), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Protein and N-linked glycoprotein biosynthesis was studied in the uninvolved epidermis of patients with psoriasis by the incorporation of radiolabelled leucine and mannose prior to and during PUVA treatment. Analysis of the polyacrylamide gel electrophoresis (PAGE) patterns of the 3[H]-labelled proteins and glycoproteins showed that the major changes in untreated uninvolved psoriatic epidermis compared to normal epidermis were: (a) a shift towards the synthesis of low-molecular-weight glycoproteins; (b) the absence of a 48-kDa peak labelled with mannose; (c) the appearance of 3[H]-mannose-labelled peaks at 40–36 kDa. PUVA treatment gradually changed the PAGE profile back more towards that expected for normal epidermis, with the reintroduction of a 52–48-kDa glycoprotein and reduction of the peaks in the 40–34-kDa region. This effect was dependent on uninterrupted treatment. The PUVA-treated PAGE profiles were compared to those expected in skin tumours (i.e. increased 3[H]-mannose-labelled peaks at 95 and 40–34 kDa with an absence of 62-kDa peaks). It appeared that these criteria were not seen generally as a result of PUVA treatment. However, the results indicate that tumour development may be possible if a patient responds to PUVA treatment by showing an increased peak at 95 and 40–34 kDa in association with a loss of an 3[H]-mannose-labelled peak at 62 kDa.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1991.tb00316.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Histocompatibility antigens in discoid and systemic lupus erythematosus (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 96 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A Study of histocompatibility (HLA) antigens in 69 patients with discoid lupus erythematosus (DLE) showed an increased incidence of HLA-B7 and HLA-B8 related to the age at onset and sex of the patient. Young females and males aged 15–39 years at onset were associated with HLA-B7and females aged over 40 years with HLA-B8. This supports previous studies concerning sex and age specific onset rates in DLE which suggested that there is more than one genotype in this disorder. Female patients with systemic lupus erythematosus (SLE) at all ages of onset showed a significant association with HLA-B8. Female patients, with onset 15–39 years, with either SLE or DLE which has transformed to SLE, show a significant increase in HLA-B8 compared with the females in the same age at onset group who have the discoid disease. The presence of HLA-B8 in a young female with DLE may represent a risk factor for the development of the systemic disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb12535.x
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Severe halogen acne due to a trifluoromethylpyrazole derivative and its resistance to isotretinoin (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 132 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb08641.x
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Information leaflets in the dermatology out-patient waiting area (1992)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 127 (1992), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Patients’attitudes to the supply and quality of information provided about their condition were examined by questionnaire before (n=852) and after exposure to an information leaflet campaign (n= 560) in the dermatology out-patient waiting area. A high expectation of this service was demonstrated, particularly from patients under 60 years of age with chronic diseases. A variety of information sources, other than doctors, were identified which could be improved (video-systems, specialist nurses, leaflets, posters). The campaign significantly increased the percentage of patients who derived information from the leaflet source (5·6–18·8%, P 〈 0·001) and it reduced a demand for leaflets (16·4–9·l%, P 〈 0·001), However, the campaign did not alter patients’perceived need to spend more time with a dermatologist. In order to achieve a greater impact on patient satisfaction, a combination of information sources in the out-patient department should be targeted at young adults with chronic diseases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1992.tb14846.x
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