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The role of catecholamines in behavioral arousal during ontogenesis (1973)

Campbell, Byron A. ; Mabry, Paul D.

Springer

Psychopharmacology 31 (1973), S. 253-264

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ISSN: 1432-2072

Keywords: Locomotor Activity ; α-Methyl-Para-Tyrosine ; Reserpine ; l-Dopa ; Ontogenesis ; Rat

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Effect of catecholamine depletion on normal hyperactivity in the neonatal rat was examined. Both α-methyl-para-tyrosine and reserpine significantly depressed behavioral arousal at 15 days postpartum, the age of greatest excitability. Heightened activity could be restored in drug-treated animals by administration of l-Dopa. These results indicate that the ontogenetic hyperactivity effect is a result of accelerated catecholamine function.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00422515

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