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  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives To define the prevalence of pelvic floor disorders in a non-institutionalised community and to determine the relationship to gender, age, parity and mode of delivery.Design A representative population survey using the 1998 South Australian Health Omnibus Survey.Sample Random selection of 4400 households; 3010 interviews were conducted in the respondents'homes by trained female interviewers. This cross sectional survey included men and women aged 15–97 years.Results The prevalence of all types of self-reported urinary incontinence in men was 4.4% and in women was 35.3% (P 〈 0.001). Urinary incontinence was more commonly reported in nulliparous women than men and increased after pregnancy according to parity and age. The highest prevalence (51.9%) was reported in women aged 70–74 years. The prevalence of flatus and faecal incontinence was 6.8% and 2.3% in men and 10.9% and 3.5% in women, respectively. Pregnancy (〉 20 weeks), regardless of the mode of delivery, greatly increased the prevalence of major pelvic floor dysfunction, defined as any type of incontinence, symptoms of prolapse or previous pelvic floor surgery. Multivariate logistic regression showed that, compared with nulliparity, pelvic floor dysfunction was significantly associated with caesarean section (OR 2.5, 95% CI 1.5–4.3), spontaneous vaginal delivery (OR 3.4, 95% CI 2.4–4.9) and at least one instrumental delivery (OR 4.3, 95% CI 2.8–6.6). The difference between caesarean and instrumental delivery was significant (P 〈 0.03) but was not for caesarean and spontaneous delivery. Other associations with pelvic floor morbidity were age, body mass index, coughing, osteoporosis, arthritis and reduced quality of life scores. Symptoms of haemorrhoids also increased with age and parity and were reported in 19.9% of men and 30.2% of women.Conclusion Pelvic floor disorders are very common and are strongly associated with female gender, ageing, pregnancy, parity and instrumental delivery. Caesarean delivery is not associated with a significant reduction in long term pelvic floor morbidity compared with spontaneous vaginal delivery.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 79 (1972), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ultrastructural changes in normal trophoblast maintained in organ culture are described. In well oxygenated conditions the fine structural integrity of the trophoblast is maintained up to 96 hours, and the tissue appears to function normally. Hypoxia quickly damages the syncytium and marked changes occur throughout the trophoblast, including apparent attempts at regeneration. These experimentally produced changes in hypoxia are very similar to the ultrastructural placental bnormalities already described in pre-eclampsia, and more so to the placental abnormalities in placental insufficiency, which are described here for the first time. These similarities suggested that hypoxia is a primary aetiological factor in these conditions rather than an effect of the primary disease process.
    Type of Medium: Electronic Resource
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