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  • 1
    ISSN: 1572-8773
    Keywords: Heavy metals ; Efflux of Na+ and K+ ; Nostoc muscorum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary This study presents the effects of Cr, Pb, Ni and Ag on growth, pigments, protein, DNA, RNA, heterocyst frequency, uptake of NH4 + and N03 −, loss of electrolytes (Na+ and K+), nitrate reductase and glutamine synthetase activities ofNostoc muscorum. The statistical tests revealed a direct positive correlation between the metal concentration and inhibition of different processes. Ni was found to be more toxic against growth, pigments and heterocyst differentiation compared to the other metals. Inhibition of pigment showed the following trend: chlorophyll 〉 phycocyanin 〉 carotenoid. No generalized trend for inhibition of macromolecules was observed. The loss of K+ and Na+ as affected by Cr, Ni and Pb was similar but more pronounced for K+ than Na+. The inhibition of physiological variables depicted the following trend: Na+ loss 〉 K+ loss 〉 glutamine synthetase 〉 NH4 uptake 〉 growth 〉 N03 − uptake 〉 nitrate reductase 〉 heterocyst frequency. This study therefore suggests that loss of electrolytes can be used as a first signal of metal toxicity in cyanobacteria. However, further study is needed to confirm whether the abnormality induced by nickel (branch formation) is a physiological or genetic phenomenon.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0428
    Keywords: Type 1 diabetes ; nephropathy ; risk factors ; HLA antigens
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study of risk factors for diabetic nephropathy in juvenile Type 1 (insulin-dependent) diabetes mellitus compares two carefully characterised groups of patients, one with proteinuria (n = 23), the other a control group (n = 24) with no evidence of nephropathy despite more than 25 years of diabetic life. No significant difference was observed between the groups in any HLA-A, -B or -DR antigen or Bf allotype. DR3 was present in 87% of patients with proteinuria and 75% of the diabetic control group; DR4 was present in 48% of patients with proteinuria and 63% of diabetic controls; BfFl was present in 17% of patients with nephropathy and 9% of the diabetic control group. Compared with the control group, patients with proteinuria had significantly higher mean diabetic-clinic blood glucose concentrations before the diagnosis of microvascular disease, a significantly earlier age at diagnosis of diabetes, and had more often been treated with once-daily as opposed to twice-daily insulin regimens. Susceptibility to nephropathy in Type 1 diabetes appears to be determined by the quality of metabolic control and age of onset of diabetes; although the number of subjects studied was relatively small no evidence was found of any influence of HLA or Bf phenotype.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-198X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 51 (1996), S. 347-347 
    ISSN: 1432-1041
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    World journal of microbiology and biotechnology 8 (1992), S. 110-114 
    ISSN: 1573-0972
    Keywords: Anabaena doliolum ; cell immobilization ; Chlorella vulgaris ; metal toxicity ; removal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Alginate-immobilized and free cells ofAnabaena doliolum andChlorella vulgaris were compared for their use in the removal and toxicity bioassays of Cu and Fe. A decrease in toxicity with regard to growth and uptake of NO 3 − and NH 4 + was noticed following immobilization of both the organisms. In contrast, immobilized cells had higher uptake rates of Cu and Fe suggesting that immobilization offers protection against metal toxicity. Compared with free cells, the immobilized cells showed greater efficiency for metal removal, even over three repeated cycles, though with a gradual decrease in efficiency in the second and third cycles. This reduction in removal efficiency was, however, more pronounced for Fe withA. doliolum and for Cu withC. vulgaris. The ease in harvesting and potential for repeated use makes the immobilized cells good tools for scavenging heavy metals from metal-contaminated environments.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 178 (1977), S. 1971-1977 
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: The mechanism of the polymerization of acrylamide in aqueous medium initiated by the glycerol (R)/Ce(IV) redox system was studied. The rate of monomer disappearance was found to be directly proportional to [M]3/2, and R1/2 at lower concentrations of Ce(IV). The rate of the disappearance of ceric ions was found to be inversely proportional to [M] and directly proportional to [Ce(IV)] and [R]. Consistent with the findings of earlier investigations, a complex formation between monomer, acrylamide, and ceric ion is indicated. The experimental results show the termination to be mutual. On the basis of these and other kinetic results, an appropriate mechanism is proposed. At higher concentration of Ce(IV), a different mechanism seems to operate. The rates of disappearance of both the monomer and ceric ions are retarded on addition of anions like HSO4-, SO4- -, or CIO4-, but they are accelerated on the addition of Mn(II) ions. Interpretations of the above observations are furnished.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    World journal of microbiology and biotechnology 9 (1993), S. 196-201 
    ISSN: 1573-0972
    Keywords: Anabaena doliolum ; calcium ; Chlorella vulgaris ; heavy metals ; immobilization ; magnesium ; organic acids ; pH
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract The potential of alginate-immobilized Anabaena doliolum and Chlorella vulgaris was assessed for removal of nutrients (NO inf3 sup- and NH inf4 sup+ ) and metals (Cr2O inf7 sup2- and Ni2+) at different biomass concentrations (0.05, 0.1, 0.25, 0.49 and 1.22 g dry wt l-1) and pH values (4 to 10). Though uptake of all these substances was higher in concentrated algal beads (0.25, 0.49 and 1.22 g dry wt l-1), their rate of uptake was significantly (P〈0.001) lower than that of low (0.05 g dry wt l-1) cell density beads. For A. doliolum, there was no significant difference in uptake rates for beads having densities of 0.05 and 0.1 g dry wt l-1. Chlorella vulgaris, however, showed maximum efficiency at 0.1 g dry wt l-1. Uptake of both the nutrients and the metals was maximal at pH 7 followed by pH 8, 6, 9, 10, 5 and 4. Of the different substances (organic acids and divalent cations) used, humic acid was most efficient in decreasing metal uptake. Mg2+ was, however, more efficient than Ca2+ in decreasing Ni2+ uptake. Immobilized algae with a cell density of 0.1 g dry wt l-1 were the most efficient for nutrient and metal removal at pH 6 to 8.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    World journal of microbiology and biotechnology 10 (1994), S. 439-443 
    ISSN: 1573-0972
    Keywords: Agar ; alginate ; Anabaena doliolum ; carrageenan ; chitosan ; Chlorella vulgaris
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Anabaena doliolum and Chlorella vulgaris immobilized on chitosan were more efficient at removing NO3 −, NO2 p−, PO4 3− and CR2O7 2− from wastewaters than cells immobilized on agar, alginate, carrageenan or even free cells. Carrageenan-immobilized cells, however, were better at removing NH4 + and Ni2+. The PO4 3− uptake capacity was significantly increased in cells starved of PO4 3− for 24 h. Agar-immobilized cells, though having good metal and nutrient uptake efficiency, had only a slow growth rate. Chitosan is recommended as an algal support for wastewater detoxification.
    Type of Medium: Electronic Resource
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