Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Thrombopoietic properties of 5-methoxytryptamine plus melatonin versus melatonin alone in the treatment of cancer-related thrombocytopenia (2001)
    Copenhagen : Munksgaard International Publishers
    Journal of pineal research 30 (2001), S. 0 
    Details
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Recent studies have shown that the hematopoietic system is under neuroendocrine control. In particular, thrombopoiesis has been proven to be stimulated by melatonin, and the pineal indole has been shown to be effective in the treatment of thrombocytopenia resulting from different causes. At present, however, there are no data concerning the possible thrombopoietic activity of pineal indoles other than melatonin. The present study was carried out to evaluate the effect of a concomitant administration of the pineal indole 5-methoxytryptamine in patients with cancer-related thrombocytopenia who did not respond to melatonin alone. The present study included 30 patients, who were randomized to receive melatonin alone (20 mg/day orally in the evening) or melatonin plus 5-methoxytryptamine (1 mg/day orally in the early afternoon). A normalization of platelet count was achieved in 5/14 (36%) patients treated with melatonin plus 5-methoxytryptamine and in none of the patients treated with melatonin alone (P〈0.05). Moreover, mean platelet number significantly increased only in the patients treated with melatonin plus 5-methoxytryptamine. This preliminary clinical study would suggest that 5-methoxytryptamine, a pineal indole, may also exert thrombopoietic activity. Further studies, however, will be required to establish whether 5-methoxytryptamine may play a direct thrombopoietic activity, or whether it may act by improving melatonin's efficacy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-079X.2001.300208.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and gabaergic drugs (1980)
    Springer
    Journal of neurology 223 (1980), S. 67-70 
    Details
    ISSN: 1432-1459
    Keywords: Post-anoxic action myoclonus ; Lance-Adams syndrome ; Levodopa ; Gaba ; Bacoflen ; Antiepileptic drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Beschrieben wird ein Fall von postanoxicher Myoklonie, der durch L-Dopa, Gaba und Bacoflen fast völlig unter Kontrolle gebracht werden konnte. Antiepileptische Medikamente scheinen nicht wirksam zu sein.
    Notes: Summary A case of post-anoxic action myoclonus is reported in which a very good control of the myoclonic jerks was achieved with levodopa, gaba and bacoflen, while the antiepileptic drugs did not seem to be useful.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313141
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Trithiozine polyneuropathy: clinical, neurophysiological and histopathological study of three cases (1981)
    Springer
    Neurological sciences 2 (1981), S. 291-295 
    Details
    ISSN: 1590-3478
    Keywords: Polyneuropathy ; trithiozine ; EMG ; biopsy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Gli Autori descrivono tre casi di polineuropatia insorta in pazienti ulcerosi e trattati per alcune settimane con Tritiozina. I quadri istopatologici osservati in due pazienti in cui si è ottenuta biopsia del nervo surale, evidenziano una sofferenza assonale del tipo della degenerazione walleriana a carico delle fibre mieliniche, specie di maggior calibro. Vengono discussi gli elementi a favore di una origine tossico-iatrogena del quadro clinico osservato.
    Notes: Abstract 3 peptic ulcer patients, treated for a few weeks with Trithiozine, developed polyneuropathy. The histopathological patterns in the 2 patients in whom sural nerve biopsy was done presented wallerian degeneration of the axons of the myelinated fibers, especially those of larger caliber. The evidence for a iatrogenic toxic etiology is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02335410
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...