ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Technical Procedures for the Synthesis of Carotenoids and Related Compounds from 6-Oxo-isophorone. VII. Synthesis of Rhodoxanthin and (3RS,3RS)-Zeaxanthin from the C15-Ring Component1An efficient 7-step synthesis of (3RS,3RS)-zeaxanthin (3) in 20% overall yield starting from 6-oxo-isophorone (7) is described. Intermediates are 6,6′-dihydro-rhodoxanthin (4) and rhodoxanthin (1), which are now accessible in 4 and 5 steps, and 45 and 25% overall yield, respectively. Novel methods for the simultaneous removal of the hydroxy group and the partial reduction of the triple bond of a monoalkynylated 1,4-dioxo-2-ene system have been developed.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19820650328
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