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  • 1
    Electronic Resource
    Electronic Resource
    Confronting Complexity: Strategies for Understanding the Microcircuitry of the Retina (2000)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 23 (2000), S. 249-284 
    Details
    ISSN: 0147-006X
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Notes: Abstract The mammalian retina contains upward of 50 distinct functional elements, each carrying out a specific task. Such diversity is not rare in the central nervous system, but the retina is privileged because its physical location, the distinctive morphology of its neurons, the regularity of its architecture, and the accessibility of its inputs and outputs permit a unique variety of experiments. Recent strategies for confronting the retina's complexity attempt to marry genetic approaches to new kinds of anatomical and electrophysiological techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.neuro.23.1.249
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The spatial filtering properties of local edge detectors and brisk–sustained retinal ganglion cells (2005)
    Oxford, UK : Blackwell Publishing Ltd
    European journal of neuroscience 22 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We compared image computation in the rabbit retina by two different cell types: the so-called ‘local edge detecting’ ganglion cells and the well-known brisk–sustained ganglion cells. From both anatomical and physiological evidence, these cells are present in nearly equal numbers and thus overlap to sample the same regions of visual space. We recorded simultaneously from overlapping cells on a dense microelectrode array. The results were analysed using an anatomically realistic simulation of the retina's processing levels. The ‘local edge detecting’ cell was found to be tuned to higher spatial frequencies and to have a narrower spatial frequency bandpass than the brisk–sustained cells. Simulation revealed that this is due primarily to the ‘zero-crossing’ detector implied by the definition of the local edge detector. The outputs of the simulations in response to complex images were analysed quantitatively. The results showed the population of local edge detectors to transmit a sparser code than the brisk–sustained cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.04390.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Synaptic contacts between an identified type of ON cone bipolar cell and ganglion cells in the mouse retina (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 21 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We surveyed the potential contacts between an identified type of bipolar cell and retinal ganglion cells in the mouse. By crossing two existing mouse strains (line 357 and line GFP-M), we created a double transgenic strain in which GFP is expressed by all members of a single type of ON cone bipolar cell and a sparse, mixed population of retinal ganglion cells. The GFP-expressing bipolar cells appear to be those termed CB4a of Pignatelli & Strettoi [(2004) J. Comp. Neurol., 476, 254–266] and type 7 of Ghosh et al. [(2004) J. Comp. Neurol., 469, 70–82 and J. Comp. Neurol., 476, 202–203]. The labelled ganglion cells include examples of most or all types of ganglion cells present in the mouse. By studying the juxtaposition of their processes in three dimensions, we could learn which ganglion cell types are potential synaptic targets of the line 357 bipolar cell. Of 12 ganglion cell types observed, 10 types could be definitively ruled out as major synaptic targets of the line 357 bipolar cells. One type of monostratified ganglion cell and one bistratified cell tightly cofasciculate with axon terminals of the line 357 bipolar cells. Double labelling for kinesin II demonstrates colocalization of bipolar cell ribbons at the sites of contact between these two types of ganglion cell and the line 357 bipolar cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.03967.x
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  • 4
    Electronic Resource
    Electronic Resource
    Vision The retina's fancy tricks (2003)
    [s.l.] : Nature Publishing Group
    Nature 423 (2003), S. 387-388 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] When the first light-sensitive amoeba drifted down a stream, it encountered one of the fundamental problems of vision, which is that the world doesn't sit still. Trees move in the breeze, grass rustles, the sun and stars drift across the sky. The most basic use of an organism's light-sensitivity is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/423387a
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Retinal direction selectivity after targeted laser ablation of starburst amacrine cells (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 389 (1997), S. 378-382 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Directionally selective retinal ganglion cells respond strongly when a stimulus moves in their preferred direction, but respond little or not at all when it moves in the opposite direction. This selectivity represents a classic paradigm of computation by neural microcircuits, but its cellular ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/38723
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    Paper (German National Licenses)
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