Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Phagocytic activity of Kupffer cells in splenectomized rats (1988)
    Springer
    Virchows Archiv 413 (1988), S. 457-462 
    Details
    ISSN: 1432-2307
    Keywords: Kupffer cells ; Phagocytic activity ; Splenectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Carbonized polyethylene microspheres of 3.53 gm diameter were injected intravenously into splenectomized, laparotomized, and untreated rats. The number of Kupffer cells which phagocytosed microspheres and the number of microspheres phagocytosed by single Kupffer cells were counted. The number of Kupffer cells which phagocytosed microspheres was 1.51 times greater in splenectomized rats than in untreated rats, and 1.29 times greater in splenectomized rats than in laparotomized rats, both values being statistically significant. Although this same value was 1.18 times greater in laparotomized fats than in untreated rats, this was not statistically significant. The number of microspheres phagocytosed by single Kupffer cells also increased significantly in splenectomized rats. The intra-acinar distribution of the phagocytosing Kupffer cells showed the number in the periportal area to be 8–9 times greater than in the central area in all 3 groups. No significant difference in this intra-acinar distribution was observed between the groups. In addition, there was no difference in the phagocytic activity of Kupffer cells and the distribution of phagocytosing Kupffer cells between the hepatic lobes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00716994
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Morphometric comparison of mitochondria and myofibrils of cardiomyocytes between hypertrophic and dilated cardiomyopathies (1990)
    Springer
    Virchows Archiv 416 (1990), S. 473-478 
    Details
    ISSN: 1432-2307
    Keywords: Cardiomyopathies ; Ultrastructure ; Morphometry ; Mitochondria ; Myofibrils
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We performed an ultrastructural, morphometric comparison of mitochondria and myofibrils of cardiomyocytes using endomyocardial biopsy specimens in hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). Biopsies came from the right ventricular side of the interventricular septum in nine patients with HCM, nine with DCM, and nine controls with arrhythmia and/or ST depression. Morphometric analysis was carried out using electron microscopic photographs and an image analyser. Mitochondria were significantly greater in number and smaller in size in HCM than in the control group. In DCM, the size of mitochondria was also significantly smaller than in the control group, although their number was similar to that of the control group. No statistically significant difference was found regarding the size of mitochondria between HCM and DCM. The percentages of both mitochondrial and myofibrillar areas in cytoplasm were smaller in the DCM than the HCM and control groups, though no difference was seen between the latter two. The ratio of mitochondrial area to myofibrillar area was almost the same in each group. These results suggest increased mitochondrial function to match hypertrophic cardiomyocytes in HCM, and decreased mitochondrial function and cardiomyocytic contractility in DCM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01600297
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Expression and localization of ossification-related factors in fracture healing: Comparative study of experimental union and non-union models (1996)
    Springer
    Journal of orthopaedic science 1 (1996), S. 193-202 
    Details
    ISSN: 1436-2023
    Keywords: fracture healing ; bone morphogenetic protein ; immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The immunohistochemical expression and localization of some ossification-related factors, including a bone growth factor (bone morphogenetic protein, BMP), non-collagenous proteins (osteocalcin, BGP; bone sialoprotein, BSP), and type II collagen, were compared in union and non-union models of fracture healing in rats. In the union model, fracture healing was seen by day 25, whereas the non-union model did not show healing even on day 32. In both models, BMP, BGP, BSP, and type II collagen were expressed mainly in chondrocytes, with proliferating cell nuclear antigen (PCNA)-positive reaction in the soft callus. In the non-union model, the expression of BMP, BGP, BSP, type II collagen, and PCNA disappeared earlier than in the union model. In fracture healing, PCNA-positive cells expressed the ossification-related factors, these being essential for ossification.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02349818
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Intracranial Low-grade Chondrosarcoma with Hyperostosis of the Skull: A Case Report (2000)
    Springer
    Journal of neuro-oncology 49 (2000), S. 249-254 
    Details
    ISSN: 1573-7373
    Keywords: intracranial chondrosarcoma ; above the skull base ; meningioma ; hyperostosis ; calcification ; intracranial chondroma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe a case of intracranial chondrosarcoma in a 46-year-old woman. The preoperative diagnosis was meningioma as plain radiography and computed tomography of the head revealed a tumor with discrete calcifications predominantly in the right frontoparietal region and hyperostosis of the inner table of the skull overlying the tumor. However, the tumor was histologically composed of cartilaginous tissue without meningiomatous differentiation and the final diagnosis was a low-grade chondrosarcoma based on its histological appearance and size, together with the radiologic images. Intracranial chondrosarcoma occurring above the skull base is extremely rare and 19 cases were found in our literature review. Intracranial chondrosarcoma showing hyperostosis of the skull has not been reported in the cases. The discussion includes its differential diagnosis, origin, and clinical behavior.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006498209279
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Peroxisomes in guinea pig liver: their peculiar morphological features may reflect certain aspects of lipoprotein metabolism in this species (1991)
    Springer
    Cell & tissue research 263 (1991), S. 145-154 
    Details
    ISSN: 1432-0878
    Keywords: Peroxisomes ; Lipid metabolism ; Lipoproteins ; Peroxisome clusters ; Morphometry ; Catalase ; Cytochemistry ; Guinea pig
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We have studied the ultrastructural characteristics and the distribution of peroxisomes in guinea pig liver using electron-microscopic cytochemistry for catalase and morphometry. By light microscopy, peroxisomes appear as dark 0.2–0.5 μm granules in the cytoplasm of liver parenchymal cells, often forming large clusters that measure up to 5 μm across. Rows of single peroxisomes or their aggregates line the sinusoidal surface of hepatocytes. Electron microscopy reveals that clusters of up to 25 individual peroxisomes are usually located in the subsinusoidal region of parenchymal cells. The mean diameter and the volume density of peroxisomes are larger in pericentral than in periportal regions of the liver lobule. Whereas large amounts of lipoprotein particles with a mean diameter of 160 nm (chylomicrons) are present in the Disse space, the cytoplasm of parenchymal cells contains multivesicular bodies and abundant lipid droplets. In addition, the Golgi complexes show distended lipoprotein-filled vesicles suggesting active biosynthesis of lipoproteins. We propose that the unique features of peroxisomes in guinea pig liver, such as cluster formation and alignment along the sinusoidal surface, may be related to the high levels of lipoproteins in the portal circulation and their hepatic catabolism in this species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00318410
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...