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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Tetrahedron Letters 13 (1972), S. 3795-3798 
    ISSN: 0040-4039
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    ISSN: 1435-0130
    Keywords: Key words Bioactive glass ceramics ; Bone substitutes ; Facial skeleton augmentation ; Congenital and acquired deformities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The reconstruction of defects of the facial skeleton resulting from congenital faults, tumor removal, or trauma should provide function and form. Synthetic bone substitutes can be used in patients in which autologous bone graft or other operative techniques are contraindicated by the patient’s condition or would not achieve the expected result. The advantages of synthetic substances are obvious: there is no secondary defect due to harvest, and surgery and healing time are therefore reduced. This, together with the shortening of operating and hospital times, reduces costs. A satisfactory result can be achieved in one surgical intervention. Implants are available in the size, volume, and shape required by the anatomical defect; in addition, they are easy to insert, can be stored for long periods, and can be resterilized if necessary. Biocompatible nonresorbable glass ceramics based on oxyfluoroapatite and wollastonite (BAS-0) have been used successfully as a filler or a bone substitute in orthopedics or in maxillofacial surgery since 1991. Surface-active inorganic polycrystalline, nonmetal biomaterial with osteoconductivity, permits osseointegration, i.e., a direct physicochemical bond between live bone tissue and the implant without formation of a fibrous capsule. Compared with hydroxyapatite, it has significantly higher durability to mechanical strain in simulated body fluid and a chemical bond with live bone tissue that is ten- to 100-fold stronger. Due to these features, this material was chosen for restoration of the facial skeletal framework in ten patients in whom other previous solutions had been unsuccessful (contour bone defect with chronic frontal sinusitis developed after open penetrating injury, bone defect after surgery associated with irradiation, significant congenital malformations of the facial skeleton, post-traumatic defects, and postsurgical deformities). The mean time of observation was 6 months. Healing occurred without any adverse reaction or side effect. Two extrusions were solved by secondary surgery. Carefully indicated application of a bone substitute can increase the patient’s quality of life and reduce surgery time and treatment costs.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 86 (1974), S. 453-454 
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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