ISSN:
1573-7330
Keywords:
in vitro fertilization
;
ultrasound
;
endometrial pattern
;
endometrial thickness
;
pregnancy
;
implantation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Purpose: Multiple studies have confirmed a lower implantation (IR) and pregnancy rate (PR) in women who exhibit a homogeneous pattern (pattern II) of the endometrium compared to a triple-line pattern (pattern I) on the day of hCG administration. However, no data are available to evaluate if patients alter their endometrial thickness and pattern between the day of hCG administration (D hCG ) and the day of oocyte retrieval (D RET ) and whether these changes adversely affect endometrial receptivity. Methods: We prospectively evaluated 86 women (mean age, 32.9 ± 3.8 years; range, 24–40 years) undergoing 103 IVF/ET cycles. Results: Pattern II was noted in 7 cycles (6.8%) on D hCG , compared to 96 cycles with pattern I (93.2%). However, 20 cycles (19.4%) had pattern II on D RET . The ongoing IR was 13.0% (3/23) in the pattern II group compared to 20.8% (76/365) in the pattern I group on D hCG (P = NS). However, a significant decrease in the ongoing IR, to 9.9% (7/71), was noted in pattern II, compared to 23.3% (71/305) in pattern I, on D RET (P = 0.019). There was no difference in age, basal FSH, peak E 2, P 4 on the day of hCG, number of oocytes, number of ET, or endometrial thickness between pregnant and nonpregnant patients, or between patients with pattern I and those with pattern II. A trend toward higher progesterone levels on D hCG was noted in women with pattern II (P = 0.078). Conclusions: Endometrial pattern, rather than thickness, on the day of oocyte retrieval appears to be an important prognosticator of endometrial receptivity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1020545120256
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