ISSN:
1573-8221
Keywords:
adaptation
;
cold
;
Na,K-ATPase
;
brain
;
kidney
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract During interrupted and prolonged (16 weeks) adaptation of rats to cold the Na,K-ATPase activity in their brain and kidneys is increased by 50–100% with no change in the affinity of the enzyme for ATP. It is suggested that an increase in the power of the triiodothyronine (T3)-dependent sodium pump in the kidneys and of the T3-independent sodium pump in the brain resulting from adaptation enables heat production to be increased during cooling of the animal.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00801777
Permalink