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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 368 (1994), S. 788-788 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR - In his article "Language for a polyglot readership" (Nature 359, 475; 1992), John Maddox raised the question of whether biblical and other Western cultural references should be avoided for non-European readers. My answer is no, as allusive writing is fun to read and motivates the reader to ...
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Enriched cultures of motor neurons were prepared from ventral spinal cords of 15-day-old rat embryos, an age at which motor neuron ceil death is occurring in the spinal cord, using a novel density gradient-panning method (see legend to Fig. 1; ref. 11). Many of the cells were large (cell body ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 201 (1985), S. 265-268 
    ISSN: 1617-4623
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary We have sequenced a 4.7 kb genomic fragment from the chromosomal region 68C of the Drosophila melanogaster wild-type strain Formosa which contains the salivary gland secretion protein genes sgs3 and sgs7. A comparison of this sequence with that from the same region of Oregon R (Garfinkel et al. 1983) shows that the major difference in this segment is a 300 bp region, corresponding to 20 of the 15 bp tandemly repeated units which compose the central coding region of sgs3 Oregon, which is absent in the Formosa strain. The order of the remaining repeated units, common to the two strains, suggests that this region is relatively stable and does not undergo frequent rearrangements or mutations. The 5′ and 3′ flanking sequences of the transcribed regions, which represent ca. seventy percent of our sequencing data, appear to be as strongly conserved as the transcribed sequences themselves. In the course of in vitro manipulations of the Formosa sequence, we have isolated two spontaneous deletions of repeated units in the coding region of sgs3 and discuss possible mechanisms leading to variation in sgs3 alleles.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 10 (1989), S. 189-197 
    ISSN: 0192-253X
    Keywords: Drosophila ; transformation ; Glue gene ; Gene cluster ; Gene regulation ; Sgs-3 ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: We reviewed studies on the developmental regulation of the 68C glue gene cluster of Drosophila melanogaster. Extensive transformation analyses of Sgs-3 have shown that four regions necessary for normal expression can be distinguished. The first ( + 10 to -50) contains the transcription start site and TATA motif. This region can be replaced functionally by corresponding sequences from the hsp70 gene, but it is sensitive to point mutations in the TATA sequence. The second region (-50 to -98) contains more than one upstream sequence that, in combination with the other elements, leads to stage and tissue-specific expression. The third region (centered at -600) contains an element that enhances transcript levels some 20-fold. The final region (between -1.65 and -2.35 kb) contains elements having modest (twofold to threefold) effects on expression, one of which is contained in the coding sequences of Sgs-7, a second member of the cluster.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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