ISSN:
1573-8221
Keywords:
Superoxide dismutase
;
hyperoxia
;
toxic action of oxygen
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The development of toxic manifestations in rats exposed to hyperoxia is accompanied by a significant decrease in the activity of erythrocytic superoxide dismutase (SOD). Incubation of hemolysates from control animals with H2O2 (10−3 M) or cumene peroxide (1.6\10−4 M) also led to a marked decrease in the initial SOD activity. The decrease in the initial SOD activity during hyperoxia is thus evidently connected with the formation of peroxidation products in the cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00785555
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