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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 63 (1994), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The expression of mRNAs encoding two members of the heat-shock protein 70 family, the constitutively-expressed heat-shock cognate (hsc70) mRNA and the strictly heat-inducible (hsp70) mRNA, was quantitated in cerebellar and hippocampal cells of rats 3 h after amphetamine-induced or heat-induced hyperthermia. Intracellular heat-shock mRNA levels in specific cell types were compared with those of total polyadenylic acid [poly(A)] mRNA or 18S rRNA in the same cell type. Levels of poly(A) mRNAs, 18S rRNAs, and hsc70 mRNAs were highest in large neurons and lowest in glia. hsp70 mRNAs were also present at highest levels in large neurons, suggesting that hsp70 mRNAs accumulated as rapidly in these cell types as they did in small neurons and glia. However, compared with levels of intracellular poly(A) mRNAs or levels of rRNAs, large neurons contained two- to 12-fold lower levels of hsp70 mRNAs than neurons of intermediate size and five- to 30-fold lower levels than glia. These results suggest that hsp70 mRNAs accumulated as rapidly in large neurons as in small neurons and glia, but that the large size of these neurons precluded intracellular hsp70 mRNA concentrations increasing as quickly. The susceptibility of large neurons to stress-induced cell death could be due, in part, to their inability to synthesize rapidly hsp70 in sufficient amounts to protect these cells from the initial molecular consequences of stress.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 72 (1998), S. 1536-1538 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have fabricated photopumped distributed feedback lasers by spin-casting thin films of the semiconducting polymer poly(2-butyl, 5-(2′-ethyl-hexyl)-1,4-phenylenevinylene) over gratings in silicon oxide. The lasers have two modes that each have a linewidth of 0.2 nm. The lasing wavelength was tuned from 540 to 583 nm by adjusting the period of the gratings. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 789-792 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We present reflectance anisotropy spectroscopy (RAS) data for aligned films of luminescent conjugated polymers. Ultrathin films (5–10 nm) spin-cast onto friction-deposited poly-tetrafluoroethylene (PTFE) show birefringence and dichroism indicating alignment of the polymer chains with the PTFE axis. The observed dichroism agrees very well with recently published polarized ultraviolet absorption spectra. In particular, the spectrum of a derivative of poly (para-phenylene) shows the onset of a perpendicular-polarized absorption feature at 5 eV, consistent with recent theoretical predictions. Thick films, prepared by gel-processing in polyethylene (PE), also show characteristic optical anisotropy, and the RAS results are interpreted in terms of the ellipsometric functions, Ψ and Δ. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 260 (1976), S. 432-433 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 Growth of B. stearothermophilus, B. licheniformis, B. megaterium and B. subtilis on glucose and aMG Incubation temperature (C) Glucose (2 mM) aMG (2 mM) Lag period (min) Doubling time (min) E480 Doubling time (min) E680 Organism B. licheniformis 37 50 0.315 ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 84 (1991), S. 505-516 
    ISSN: 1432-1106
    Keywords: Monkey ; Inferior temporal cortex ; Cross-correlation ; Visual cortex
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Functional interactions among inferior temporal cortex (IT) neurons were studied in the awake, fixating macaque monkey during the presentation of visual stimuli. Extracellular recordings were obtained simultaneously from several microelectrodes, and in many cases, spike trains from more than one neuron were extracted from each electrode by the use of spike shape sorting technology. Functional interactions between pairs of neurons were measured using cross-correlation. Discharge patterns of single neurons were evaluated using auto-correlation and PST histograms. Neurons recorded on the same electrode (within about 100 μn) had more similar stimulus selectivity and were more likely to show functional interactions than those recorded on different electrodes spaced about 250 to 500 microns apart. Most neurons tended to fire in bursts tens to hundreds of milliseconds in duration, and asynchronously from the stimulus induced rate changes. Correlated neuronal firing indicative of shared inputs and direct interactions was observed. Occurrence of shared input was significantly lower for neuron pairs recorded on different electrodes than for neurons recorded on the same electrode. Direct connections occurred about as often for neurons on different electrodes as for neurons on the same electrode. These results suggest that input projections are usually restricted to less than 500 μm patches and are then distributed over greater distances by intrinsic connections. Measurements of synaptic contribution suggest that typically more than 5 near-simultaneous inputs are required to cause an IT neuron to discharge.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal of Numerical Modelling: Electronic Networks, Devices and Fields 4 (1991), S. 123-138 
    ISSN: 0894-3370
    Keywords: Engineering ; Electrical and Electronics Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Notes: Computer models in electromagnetics are based primarily either on integral or on differential equations. The former arise from source integrals using some appropriate Green's function whereas the latter originate from the Maxwell curl equations. Although requiring volume rather than surface sampling even for spatially homogeneous problems, in contrast to integral-equation (IE) models, differential-equation (DE) models are geneally a better choice for problems involving spatial inhomogeneities. This is because such problems require volumetric sampling using either approach, but the DE model produces a sparse matrix rather than the full matrix of the IE formulation.In this paper we describe a new approach based on using multiply propagated fields for numerically solving the banded matrix that results from discretizing the Helmholtz equation. A computer-time savings of N1/2 and N2/3 for two-dimensional (2-D) and three-dimensional (3-D) problems, respectively, is made possible, where N is the total number of field samples or unknowns. For even moderate-size problems where 100 samples per linear dimension are used (N2 = 10,000 and N3 = 1,000,000), the time savings can be of the order of 100 and 10,000 respectively. Another advantage of this procedure, which we call Helmholtz equation multiple propagator (HEMP), is that the radiation or closure condition needed to terminate the spatial solution mesh for exterior problems can be enforced rigorously with essentially no additional computational cost.The method is illustrated for a 2-D problem by application to plane-wave scattering from an infinite, metal, circular cylinder. Results are presented for the mode amplitudes of the scattered field, the induced surface current, and the bistatic far field as obtained from HEMP, and shown to be in good agreement with the analytical results. Although limited here to the simplest possible application in order to establish its feasibility, the approach's advantage would be its applicability to 2-D and 3-D problems involving inhomogeneous, penetrable objects.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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