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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 23 (1971), S. 367-372 
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Adriamycin ist ein echter, antiblastisch wirkender Stoff. Es entwickelt seine Aktivität mit der Zunahme der Nukleinsäuresynthese und verursacht als Folge das frühzeitige Absterben der Zellen einschließlich der Lymphozyten. Der Asparaginaseeffekt ist einem enzymatischen Mechanismus zuzuschreiben, der den Lymphozyten eine Aminosäure (L-Asparagine) vorenthält, die für das Washstum und die Aktivierung der Lymphozyten wichtig ist, ohne jedoch einen Zellschaden zu verursachen.
    Notes: Summary Adriamycin is a substance with truly antiblastic effect. Its activity is developed with the increase of the nucleic acid synthesis. Therefore Adriamycin causes the early death of cells inclusion of lymphocytes. The effect of L-asparaginase is due to an enzymatic effect by retention of L-asparaginase to the lymphocytes for their growth and activity. A cellular damage of the lymphocytes cannot be established.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 150 (1991), S. 481-482 
    ISSN: 1432-1076
    Keywords: Newborn infant ; PMN chemotaxis ; Caesarean section delivery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We evaluated polymorphonuclear leucocyte (PMN) chemotaxis and cortisol levels in cord blood from 15 healthy term infants delivered by caesarean section and from 15 healthy vaginally delivered term infants. Mean neutrophil chemotaxis was significantly higher in infants delivered by caesarean section (78.3±23.4μm) than in vaginally delivered infants (57.8±16.6 μm;P=0.01). Mean blood cortisol level was significantly lower in infants delivered by caesarean section (9.14±2.76 μg/dl) than in infants born by vaginal delivery (20.71±6.98 μg/dl;P=0.0001). No relationship was found between PMN chemotaxis and blood cortisol level. The higher neutrophil chemotactic activity observed in infants delivered by caesarean section could be related to general maternal anaesthesia.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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