ISSN:
1432-0584
Keywords:
Keywords Thrombotic thrombocytopenic purpura
;
Antibiotics
;
Plasma infusion
;
Drug-induced colitis
;
Drug eruption
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract An 81-year-old man was admitted to the hospital with a fever and loss of appetite. After treatment with piperacillin sodium (PIPC), the patient exhibited thrombocytopenia, hemorrhagic colitis, and drug-induced skin eruption. On the fifth day after PIPC induction, he further experienced neurological abnormalities, such as disorientation and confusion, renal dysfunction, and microangiopathic hemolytic anemia (MAHA). The patient was diagnosed with thrombotic thrombocytopenic purpura (TTP) on the basis of thrombocytopenia, MAHA, renal dysfunction, fever, and neurological abnormalities. Infusion of fresh-frozen plasma was initiated for treatment. His condition improved markedly after this treatment. It is rare for TTP to be accompanied with hemorrhagic colitis and skin eruption. These symptoms were induced by PIPC and were successfully treated with plasma infusion.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002770000195
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