ISSN:
1434-193X
Keywords:
Mechanical bonding
;
Interlocked molecules
;
Template synthesis
;
Calixarenes
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of the amide-based rotaxane 7a bearing calix[4]arene blocking groups is described for the first time. While rotaxane formation fails if a calix[4]arene is functionalized at the upper rim with only an amino or methylamino group lacking any spacer, the prolonged amine 5a works successfully as stopper unit preventing dethreading of the dimeric wheel 1a by its size. Rotaxane formation of 8b was observed only by MALDI-TOF mass spectrometry of the reaction mixture of the amine 5b, the axle 6 and 1a. With the larger trimeric wheel 1b no stable rotaxane could be obtained. It either does not act as a concave template or its opening is too wide, even for the bulky calixarene stoppers.
Type of Medium:
Electronic Resource
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