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  • 1
    Electronic Resource
    Electronic Resource
    Laser Assisted Formation of a Wear Resistant SiC-Metal Composite on the Surface of a Structural Aluminium Alloy (1991)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 46-47 (Jan. 1991), p. 415-424 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/58/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.46-47.415.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Applications of laser for ceramic alloying on metallic surfaces (1989)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 11 (1989), S. 495-502 
    Details
    ISSN: 0392-6737
    Keywords: Other topics in electrical properties of surfaces, interfaces and thin films
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary Ceramic and metallic materials were alloyed and cladded on a C40 steel by means of a CO2 laser heat source. The main objectives of the research were to obtain a surface modification of the C40 steel in order to increase its wear resistance and to develop a repeatable coating process of potential industrial application. In the following sections, the laser coating process (including experimental equipment and working parameters) and the most important metallurgical results are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02450997
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  • 3
    Electronic Resource
    Electronic Resource
    Bromsulphalein (BSP) kinetics in the rat: A new approach in evaluating experimental hepatotoxicity (1982)
    Springer
    International archives of occupational and environmental health 51 (1982), S. 73-79 
    Details
    ISSN: 1432-1246
    Keywords: Hepatotoxicity ; Bromsulphalein ; Carbon tetrachloride ; α-naphthylisothiocyanate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An animal model for the identification and definition of toxic liver damage, based on the investigation of the BSP metabolism in the rat is proposed. Different hepatotoxins can induce specific functional alteration on the different steps of the BSP hepatobiliary transport, mainly the uptake by hepatocytes and the biliary excretion. Removal curves of BSP from the plasma compartment as well as the biliary secretion were evaluated in rats treated with either α-naphthylisothiocyanate (ANIT) for metabolic cholestasis, or with carbon tetrachloride (CCl4) for fatty infiltration and necrosis of the liver. The data were compared with those obtained with untreated rats and with animals submitted either to complete or incomplete mechanically induced cholestasis. Our results lead to the conclusion that a satisfactory discrimination among different types of liver damage may be obtained when only two plasma parameters of BSP metabolism are considered: the disappearance rate for the early 5 min (K), and 15-min plasma BSP retention (R15). The model is proposed as a suitable tool for the evaluation of experimental hepatotoxicity in living rats giving a characterisation of the functional alteration and a measure of liver impairment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00378412
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  • 4
    Electronic Resource
    Electronic Resource
    A sequential protocol for the optimization of diagnostic procedures in hepatology (1984)
    Springer
    Journal of medical systems 8 (1984), S. 73-85 
    Details
    ISSN: 1573-689X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this paper is to present a sequential protocol to be used in clinical practice for the detection of liver diseases, based on clinical history, physical examination, and laboratory investigation. The evaluation of the protocol efficacy was carried out on a sample of 288 subjects (92 normal, and 196 affected by various liver alterations) by comparing the obtained results with reference classifications independently performed on the basis of all available subject records (including many more laboratory tests than the ones used in the protocol). A cost-benefit analysis ws also carried out, based on the resident population of Regione Piemonte, comparing the protocol with two other simpler ones. Results show that the proposed protocol allows a considerable reduction of costs, showing a high estimated efficacy for clinical use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02221871
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  • 5
    Electronic Resource
    Electronic Resource
    Studies on the maximal hepatic sulfobromophthalein removal rate (1963)
    Springer
    Digestive diseases and sciences 8 (1963), S. 251-266 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The hepatic removal of BSP from the blood during continuous intravenous infusion was calculated. The technic adopted in these researches has achieved results which complete and partly modify previously published conclusions. By using very variable rates of infusion, the existence of two different patterns could be demonstrated. The first involves the mechanism of removal of BSP from the blood when the rate of infusion is less than 25 mg. per minute, in normal subjects. In these circumstances the rate of removal is strictly correlated with the dose infused. When the rate of infusion is more than 25 mg. per minute, the rate of removal does not increase further. The removal rate thus obtained, which is usually not greater than 20 mg. per minute, therefore expresses a maximal capacity which, from the findings of the present investigation, can be defined as the “maximal removal capacity” for BSP. The existence of this phenomenon is important for two reasons. In the first place, the hypothesis that the uptake of BSP from the plasma by the liver is due simply to the diffusion of the dye into the liver cells now seems improbable, and an active role of the liver, possibly through a process of conjugation of BSP, seems more likely. In the second place, investigation of the maximal removal capacity represents a quantitative method for determination of the amount of functioning liver tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02232324
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  • 6
    Electronic Resource
    Electronic Resource
    New results on saturation phenomena in BSP metabolism: the role of free and conjugated BSP (1981)
    Springer
    Medical & biological engineering & computing 19 (1981), S. 707-716 
    Details
    ISSN: 1741-0444
    Keywords: BSP models ; Hepatic removal rate ; Liver maximum capacity ; Relative storage capacity ; Secretory transport maximum ; Wheeler-test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The fact that the role of conjugation cannot be neglected in the definition and evaluation of the different maximal transfer rates introduced in the literature (Tm, Lm) is demonstrated. Free and conjugated BSP were measured both in blood and bile during constant infusion of free BSP in man. These data proved very useful to develop a careful model of BSP metabolism able to interpret all major known facts in saturation conditions. The model shows that, in the conditions used for the Wheelter-test, biliary excretion is saturated both for free and conjugated BSP. At higher infusion rates, there is also saturation of the hepatic uptake of conjugated BSP. No other processes are saturated in these conditions. Lastly, free and conjugated BSP are excreted at a maximal rate that is not dependent on their respective amounts in the liver; this suggests the existence of independent transport mechanism in biliary excretion for free and conjugated BSP during the infusion of free BSP.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441332
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