Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of oral pathology & medicine
15 (1986), S. 0
ISSN:
1600-0714
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Langerhans cells (LCs) are dendritic cells usually present in the suprahasal regions of squamous epithelial remarkable by the presence of Fc IgG and C3 receptors, Ia/Or, T-6 and T-4 antigens on their membranes. Conventional and immunohistochemical techniques for identification of LCs require special fixation procedures and are incompatible with paraffin embedding. A method for staining LCs, in routine fixed and paraffin-embedded material, based on the use of antiserum against S-100 proteins is presented. The problem arising from the simultaneous staining of melanocytes is discussed. S-100 positive dendritic cells should be considered as LCs when fulfilling 3 criteria: 1) located in the suprabasal layers of the epithelium: 2) the whole cell body being visible: 3) with at least one dendritic process.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1600-0714.1986.tb00650.x
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