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  • 1
    Electronic Resource
    Electronic Resource
    Presacral epidermal cyst found in an adult male with a high CEA content: Report of an unusual case (1994)
    Springer
    Surgery today 24 (1994), S. 556-560 
    Details
    ISSN: 1436-2813
    Keywords: presacral tumor ; epidermal cyst ; CEA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 63-year-old Japanese man presented with constipation, having noticed flat stools for several years. Digital examination of the rectum, followed by barium enema, colonofiberscopy, computed tomography (CT), and magnetic resonance imaging (MRI) revealed an oval mass located between the retrorectal and presacral space without any mucosal lesion. This mass had narrowed the rectal lumen by compressing the rectum anteriorly. Although the plasma levels of the tumor markers were within the normal range, those of the tumor contents were elevated with a carcinoembryonic antigen (CEA) of 118 ng/mL, while the alpha-fetoprotein (AFP) value was 1 ng/mL. The tumor was completely extirpated through an abdominal incision, and there has been no evidence of recurrence thus far. Histological examination showed that the tumor wall was made of keratinized stratified squamous epithelium without any cutaneous adnexal structure, and hence it was diagnosed as an epidermal cyst. CEA was identified in these benign epithelial cells by immunoperoxidase staining using a monoclonal antibody. To the best of our knowledge, there have been only four other cases with a presacral epidermal cyst documented in the Japanese literature, all of whom were female. Our patient is the first reported case of an adult male with a presacral epidermal cyst.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01884579
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Surgical significance of dilatation of the common bile duct—With special reference to choledocholithiasis (1980)
    Springer
    Surgery today 10 (1980), S. 296-301 
    Details
    ISSN: 1436-2813
    Keywords: bile duct stone ; bilirubin stone ; cholesterol stone ; congenital choledochal cyst ; choledochoenterostomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Diameter of the common bile duct was measured in 3,119 patients who underwent primary operation for gallstones, during the period from 1975 to 1978. Although dilatation of the common bile duct was most marked in patients with bilirubin stones in the bile duct alone, dilatation was also observed in patients with cholesterol stones in the gallbladder alone. Drip infusion cholangiograms of 84 healthy patients showed that the common bile duct dilated in parallel with aging. A review of patients with congenital choledochal cysts reported in the literature in Japan revealed that few had gallstones. Thus, it was difficult to determine whether common bile duct dilatation was the cause or result of gallstones, and it was suggested that the socalled drainage operation such as choledochoenterostomy should be done only under strict indications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02468791
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Intrapleural adaptive immunotherapy for breast cancer patients with cytologically-confirmed malignant pleural effusions: an analysis of 67 patients in Kyoto and Shiga Prefecture, Japan (1993)
    Springer
    Breast cancer research and treatment 27 (1993), S. 203-210 
    Details
    ISSN: 1573-7217
    Keywords: adoptive immunotherapy ; breast cancer ; chemotherapy ; interleukin-2 ; OK-432 ; pleural effusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Sixty-seven breast cancer patients with cytologically-confirmed malignant pleural effusion, who required intrapleural treatment, were analyzed retrospectively. The patients received their first thoracentesis between 1980 and 1990. Among them, 29 patients received intrapleural administration of OK-432, a streptococcal preparation, followed by the transfer of autologous pleural effusion lymphocytes cultured with interleukin-2. Other intrapleural treatments consisted of OK-432 alone (12 patients), chemotherapeutic agents alone (n = 9), a combination of OK-432 and chemotherapy (n = 16), or others (n = 1). Twenty-six of the 29 patients given OK-432 plus cultured effusion lymphocytes responded, while only 15 of the 38 patients who received other treatments did (p 〈 0.01). Median survival time and 5-year survival rate of patients who received OK-432 and cultured lymphocytes was 12 months and 36%, while those of the patients who received other treatments was 3 months and 0%, a significant (p〈 0.001) difference in survival. Multivariate analysis using Cox's proportional hazard model revealed that the treatment (adoptive immunotherapy) was the most significant (p 〈 0.005) factor to prolong the survival of the patients among several prognostic factors. Thus, OK-432 and adoptive immunotherapy is a promising therapy that should be further evaluated in a prospective study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00665690
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Severe complications of mediastinal pancreatic pseudocyst: report of esophagobronchial fistula and hemothorax (2000)
    Springer
    Journal of hepato-biliary-pancreatic surgery 7 (2000), S. 86-91 
    Details
    ISSN: 1436-0691
    Keywords: Key words: chronic pancreatitis, pancreatic pseudocyst, hemothorax, esophagobronchial fistula, radical surgical treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We report two patients with alcoholic pancreatic pseudocyst which communicated to the mediastinal space through the aortic hiatus, in one patient resulting in hypotensive shock due to hemothorax, and in the other, resulting in esophagobronchial fistula via the mediastinal cyst. The first patient was successfully treated by radical resection of the pancreatic body and tail, and the spleen, with an ultrasonic scalpel, although inflammatory changes caused by pancreatitis were so prominent that the splenic vein was occluded. The second patient could not be treated surgically, because the superior mesenteric vein had been occluded by chronic pancreatitis; he died of respiratory failure and sepsis due to aspiration pneumonia, despite receiving medical treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005340050159
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  • 5
    Electronic Resource
    Electronic Resource
    Extrahepatic large hepatocellular carcinoma with peritoneal dissemination: multimodal treatment, including four surgical operations (2000)
    Springer
    Journal of hepato-biliary-pancreatic surgery 7 (2000), S. 339-344 
    Details
    ISSN: 1436-0691
    Keywords: Key words: hepatocellular carcinoma (hepatoma) ; extra-hepatic growth ; extrahepatic drainage vein ; spontaneous tumor bleeding ; peritoneal dissemination ; multimodal treatment ; systemic chemotherapy ; repeat hepatectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: We report a patient with extrahepatically growing large hepatocellular carcinoma (HCC) associated with dis-seminated intraabdominal tumor and spontaneous tumor bleeding who was treated with four operations, transcatheter arterial embolization, systemic chemotherapy, and hyperthermia. It took 12 months for the multimodal treatment to normalize the alpha-fetoprotein (AFP) level, and remission continued for 6 months. We performed the fourth surgical treatment for a recurrent abdominal tumor involving the small intestine and mesentery, but the patient died 26 months after the first admission. Multimodal treatment, including repeat surgical treatments, for such advanced HCC should be encouraged, to prolong life and to maintain quality of life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005340070060
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    Paper (German National Licenses)
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