ISSN:
1471-0528
Quelle:
Blackwell Publishing Journal Backfiles 1879-2005
Thema:
Medizin
Notizen:
Summary. Plasma levels of two endogenous opioid peptides, β-endorphin and met-enkephalin, as well as immunoreactive N-terminal β-lipotrophin (N-LPH) were studied in normal pregnant women from 8 to 41 weeks gestation. A total of 116 samples were assayed for β-endorphin-like immunoreactivity (C-LPH), 103 for N-LPH and 75 for met-enkephalin. Plasma β-endorphin-like immunoreactivity and N-LPH levels rose progressively throughout gestation and reached a maximum at term. Plasma met-enkephalin immunoreactivity did not significantly change throughout pregnancy. These results reflect an increasing and consistent adreno-corticotrophin (ACTH)/β-LPH and β-endorphin secretion throughout pregnancy, while the unchanged met-enkephalin levels are compatible with its known derivation from a separate precursor system.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1111/j.1471-0528.1983.tb08963.x
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