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  • 1
    Electronic Resource
    Electronic Resource
    Über den Nachweis von HIV-Antikörpern in Blutspuren (1989)
    Springer
    International journal of legal medicine 102 (1989), S. 487-493 
    Details
    ISSN: 1437-1596
    Keywords: HIV-antibodies in bloodstains ; HIV-Antikörper in Blutspuren
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Es wurden Blutspuren auf Baumwolltextil asserviert und bei Raumtemperatur gelagert. Diese Proben wurden im HIV-ELISA und -Western Blot untersucht. Dabei gelang ein HIV-Antikörpernachweis an bis zu vier Monate alten Proben.
    Notes: Summary Blood samples were collected on cotton wool and stored at +20°C. These samples were tested in an enzyme linked immunosorbent assay and the immunoblotting test. HIV-antibodies could be detected in samples stored up to four month.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00204079
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Interferon-gamma treatment in mice experimentally infected withTrichinella spiralis (1991)
    Springer
    Parasitology research 77 (1991), S. 437-442 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Interferon-τ (IFN-τ) treatment ofTrichinella spiralis-infected BALB/c mice was investigated. The therapeutic regimen consisted of daily intraperitoneal injection of 104 U murine IFN-τ for 7 days, starting at 2 weeks post-infection. Striated muscle samples (diaphragm, thigh) were collected at 4, 8 and 12 weeks after infection. The muscle larval burden, the degree of encystation and the digestion ofT. spiralis larvae were investigated. Furthermore, immunohistochemical studies of the inflammatory cell infiltrate around encysted larvae were performed. The results demonstrated an influence of IFN-τ treatment on the CD4+ and CD8+ subset distribution during the immune response but revealed no difference in the degree of encystation or digestion of encapsulated larvae as compared with control values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00931641
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Antibody response inPlasmodium vinckei malaria after treatment with chloroquine and adjuvant interferon-γ (1992)
    Springer
    Parasitology research 78 (1992), S. 629-634 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The antibody response of mice infected withPlasmodium vinckei after treatment with chloroquine either alone or in combination with interferon-γ (IFN-γ) was determined. Sequential serum samples were drawn from BALB/c mice receiving either 240 μg chloroquine on the day of infection or 120 μg chloroquine plus 104 units IFN-γ daily for 11 days beginning on day 3 prior to infection. Mice treated with additional IFN-γ showed an early induction of IgG2a response and a reduction in IgG1 antibodies as detected by the immunofluorescence technique at between 10 and 16 days after infection as compared with mice treated with chloroquine alone. Thus, IFN-γ may partly exert its antimalarial activity via the induction of IgG2a antibody formation. At 4–6 weeks after infection, when mice from both groups resisted homologous re-infection, the predominant antibody isotypes found in both groups were IgG1 and IgG2a. Serum samples obtained from mice in both treatment groups at 6 weeks after infection were used for serum transfer experiments. When parasitised erythrocytes were preincubated with such immune serum, a retardation of the course of parasitaemia by 2 days was observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00931511
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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