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  • 1
    Electronic Resource
    Electronic Resource
    Differential effect of benzodiazepine sedation in high and low anxious patients in a “real life” stress setting (1986)
    Springer
    Psychopharmacology 88 (1986), S. 226-229 
    Details
    ISSN: 1432-2072
    Keywords: Benzodiazepine ; Temazepam ; Diazepam ; Stress ; Anxiety ; Oral surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a randomised, double-blind, parallel groups study, 40 patients referred for surgical removal of impacted third molars received either (a) temazepam 40 mg orally followed at 35 min by IV saline or (b) oral placebo followed by IV diazepam 10 mg (Diazemuls). Patients were divided into High-Anxious and Low-Anxious groups by median split of their anxiety scores on the Speilberger State Anxiety Scale at the time of oral medication. Compared with placebo, temazepam significantly attenuated anticipatory anxiety in the High-Anxious group while in the Low-Anxious group no difference was found between the treatments. Preoperative but not intraoperative heart-rate distinguished between the High-Anxious and Low-Anxious groups and neither oral temazepam nor IV diazepam abolished the heart-rate response to the traumatic stages of the surgical procedure. The results are interpreted as providing support in a “real life” human stress setting for Gray's neuropsychological model of anxiety.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00652245
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Benzodiazepine - induced event amnesia following a stressful surgical procedure (1987)
    Springer
    Psychopharmacology 91 (1987), S. 244-247 
    Details
    ISSN: 1432-2072
    Keywords: Midazolam ; Diazepam ; Event amnesia ; Stress ; Surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a randomised, double-blind, parallel groups study, 40 patients undergoing surgical removal of impacted third molar teeth received either midazolam 15 mg orally followed at 35 min by intravenous saline or oral placebo followed by intravenous diazepam 10mg (Diazemuls). Episodic (event) memory was assessed by showing patients photographs of dental and neutral objects both before and after sedation and by testing subsequent recognition at 1 week. Recall of actual surgical events was assessed by questionnaire. Both treatments induced significant amnesia for visual stimuli and for surgical events. However, the degree of amnesia was more profound for artifical stimuli and no relationship was found between the extent of amnesia for the two types of event. Drilling of bone was found to provoke the greatest cardiovascular stress response and a significant relationship was found between the degree of cardiovascular activation and subsequent memory for drilling. It is concluded that the extent of benzodiazepine-induced event-amnesia may be modified by cognitive factors and especially by the extent to which the event is cognitively encoded and elaborated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217072
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Development of a direct weighting procedure for quality of life domains (1997)
    Springer
    Quality of life research 6 (1997), S. 301-309 
    Details
    ISSN: 1573-2649
    Keywords: Key words: Quality of life ; measurement ; decision making ; individual preferences.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Schedule for the Evaluation of Individual Quality of Life allows individuals to nominate the domains they consider most important to their quality of life and to use their own value system when describing the functional status and relative importance of those domains. The weights for domain importance are derived through a procedure called judgement analysis. As judgement analysis is impractical for individuals with cognitive impairment and in many clinical situations, a shorter, direct weighting procedure has been developed. To test the new procedure, 40 healthy individuals completed both direct and judgement analysis weightings, at t1 and 7-10 days later (t2). After a further 7-10 days (t3), they were asked to identify the weight profiles they had previously produced using each method. The weights produced by the two methods differed on average by 7.8 points at t1 and 7.2 points at t2. The direct weights changed on average by 4.5 points from t1 to t2, while the judgement analysis weights changed by 8.4 points. At t3, 55% of individuals were able to identify the direct weights they had previously produced. The new procedure demonstrates stability and validity but is not interchangeable with judgement analysis. The most appropriate ways of using and interpreting both procedures are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018423124390
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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