ISSN:
1432-1076
Keywords:
Key words CD2
;
CD4
;
CD8
;
CD19
;
Children
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Peripheral blood lymphocyte subsets were examined in 233 healthy school children aged 4.9–13.7 years at the time of examination. Lymphocyte subsets were characterized according to the following cluster of differentiation (CD) numbers: CD2, CD4, CD8 and CD19 and quantified according to both their absolute number and as a percentage of total lymphocytes. For the purpose of analysis, the LMS (lambda, mu, sigma) method was utilized, with a 3%–97% confidence interval. Smoothing of the generated curves, was by multiple regression analysis, using the least squares method. The results of these analyses indicate distinct trends as a child ages, both in absolute numbers and in the precentage of each cell type. Conclusion We characterized lymphocyte subsets in children aged 4.9–13.7 years. These data should prove of considerable value to pediatricians dealing with patients with known or suspected immunological problems, and ought to be used in place of the commonly used, but inappropriate, adult lymphocyte subset ranges.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01957900
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