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  • 1
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 317-318 (Aug. 2006), p. 517-520 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We have been trying to find new oxide compounds with large thermalexpansion coefficients and low thermal conductivities by means of a materialcalculation technique. Among thousands of compounds in the databases, we found thatthere were some materials with low thermal conductivities and large thermal expansioncoefficients in the group of strontium-niobium oxides. For example, Sr4Nb2O9 has athermal expansion coefficient of 14.5[removed info]10-6 /[removed info] and thermal conductivity of 1.0 W/mK,although a slight amount of other phases appear during long-term annealing. Thesethermal properties are better than those of yttria-stabilized zirconia, which is thestandard material for thermal barrier coatings. To prevent the precipitation of otherphases, we prepared the solid solutions, Sr4Nb2-xMxO9. In this study, the thermalconductivities and thermal expansion coefficients of these solid solutions weremeasured, and their thermal stabilities were evaluated by long-term annealing
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-7799
    Keywords: hepatitis C virus ; membranoproliferative glomerulonephritis ; cryoglobulin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background We determined the incidence of hepatitis C virus (HCV)-related glomerulonephritis in Japan and the glomerular localization of HCV-related antigens in this disorder. Methods We analyzed urinalysis findings in 100 consecutive Japanese patients with HCV chronic liver disease from 1993 to 1994. Immunohistochemical analysis using monoclonal or polyclonal antibodies to HCV-core antigen and polyclonal antibodies to HCV-envelope antigen was done on kidney specimens from 11 of 29 patients with antibody to HCV (anti-HCV-Ab). Results Eight of 100 patients had proteinuria, but only 2 cases (2%) were related to HCV nephropathy. Pathohistologic analysis showed 10 patients to have hepatic glomerulosclerosis, and 9 patients had mesangial proliferative glomerulonephritis involving primary immunoglobulin A nephropathy. Membranoproliferative glomerulonephritis was seen in 4 biopsy specimens that showed subendothelial electron-dense deposits and annular structures with characteristic cryogloblin. HCV core antigen was detected along the capillary walls with the same pattern as that of immunoglobulin G deposition and electron-dense deposits in 5 of 6 specimens from patients with both anti-HCV-Ab and HCV ribonucleic acid positive in the sera, but could not be detected in any of 3 specimens, from patients with anti-HCV-Ab but no HCV ribonucleic acid. Envelope antigen was not detected in the glomeruli of any specimens. Conclusions Glomerular lesions associated with HCV infection were characterized by deposition of immune complexes containing HCV core antigen and immunoglobulin G, and by the subendothelial deposition of cryoglobulin. These HCV-related glomerular diseases are rare in Japan (2% incidence), and these lesions should be distinguished from hepatic glomerulosclerosis related to advanced liver disease and other primary glomerular diseases.
    Type of Medium: Electronic Resource
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