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  • 1
    Electronic Resource
    Electronic Resource
    Immunohistochemical localization of types I, II, and III collagens in the ossified posterior longitudinal ligament of the human cervical spine (1983)
    Springer
    Calcified tissue international 35 (1983), S. 159-163 
    Details
    ISSN: 1432-0827
    Keywords: Anticollagen antibodies ; Collagen types ; Immunohistochemistry ; Ossified posterior longitudinal ligament
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Summary Immunohistochemical localization of types I, II, and III collagen in the ossified posterior longitudinal ligament of the cervical spine was studied using type-specific anticollagen antibodies. In contrast to the normal ligament which contains both types I and III collagens, the ossified matrix, composed of lamellar bone, contains only type I collagen, except for Haversian canals where type III is located in the inner wall. In the transitional region of preossifying ligaments, types III and I are both present. Type II collagen is present in the hyperplastic matrix of the ligament, and cartilage-like cells surrounded by type II collagen are aligned along nonossified ligaments adjacent to the preossifying region. A possible mechanism of matrix transition during the ossification process is given attention.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02405024
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  • 2
    Electronic Resource
    Electronic Resource
    Residual deformities related to arthrotic change after Perthes' disease (1985)
    Springer
    Archives of orthopaedic and trauma surgery 104 (1985), S. 7-14 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to clarify the long-term results of Perthes' disease and to elucidate the residual deformities, including those of the acetabulum, related to coxarthrosis, 51 patients who had had Perthes' disease were studied clinically and radiologically. Altogether there were 56 affected hips and radiographs taken from onset of disease to maturity were available in all cases. They were followed up for an average of 18 years. Thirteen hips (23%) revealed coxarthrosis. Head deformity, steepness of the lateral edge of the acetabulum, and insufficient acetabular coverage of the femoral head were noted in them both in adulthood and in the active phase of disease. Among these deformities, steepness of the lateral edge of the acetabulum was found to be the most significant prognostic factor and led to coxarthrosis of the affected hip even in the younger adult. Acetabular roof angle, which is a newly designed radiographic measurement, is a good indicator of the prognosis in Perthes' disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00449949
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  • 3
    Electronic Resource
    Electronic Resource
    Anterior transfer of the toe flexors for equinovarus deformity of the foot (1980)
    Springer
    International orthopaedics 4 (1980), S. 225-229 
    Details
    ISSN: 1432-5195
    Keywords: Spastic equinovarus ; Tendon transfer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Le transfert antérieur des longs fléchisseurs des orteils a été utilisé pour corriger la déformation en varus équin du pied spastique, tant chez l'adulte que chez l'enfant. Chez l'adulte, il s'agissait d'hémiplégies secondaires à un accident vasculaire cérébral, d'hémiplégies spastiques dues à une paralysie cérébrale, et de paraplégies médullaires spastiques. La plupart des enfants étaient atteints de paralysie cérébrale. Le transfert a paru indiqué en présence d'un pied varus équin avec fléchisseurs des orteils actifs, entraînant soit une griffe des orteils au cours de la phase pendulaire de la marche, soit une attitude en marteau irréductible. Cinquante-six malades ont été suivis plus de quatre ans. Dans tous les cas la correction du varus équin a été obtenue et s'est maintenue. Grâce à une correction satisfaisante, la stabilité de la cheville a été améliorée, les anomalies posturales au cours de la marche ont diminué et l'appareillage est devenu inutile. Ce travail démontre la supériorité du transfert des longs fléchisseurs des orteils chez de tels malades. La longueur des tendons utilisables permet de les transposer aisément sur la face dorsale du métatarse. La suppression de l'activité de muscles spastiques entraîne une amélioration de la marche et préserve la fonction des muscles jambiers antérieur et postérieur.
    Notes: Summary Anterior transfer of the long toe flexors was carried out for the treatment of spastic equinovarus foot deformity in both adults and children. Adults included those with hemiplegia subsequent to a stroke, spastic hemiplegia due to cerebral palsy and spastic spinal paraplegia. Most of the children had cerebral palsy. The transfer was indicated for an equinovarus foot with persistent activity of the toe flexors, which produced curling of the toes in the swing phase of the gait or a fixed hammer toe deformity. Fifty six patients were followed up for more than four years. In all cases correction of the equinovarus deformity was achieved and maintained. With satisfactory correction stability of the ankle improved, postural abnormalities during gait decreased and bracing was not required. This study demonstrates the advantage of the long toe flexors for muscle transfer in these patients. The length of tendon available permitted easy transfer to the metatarsal. The defunctioning of the spastic muscles allowed gait improvement and function of the tibialis posterior and tibialis anterior was preserved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00268160
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  • 4
    Electronic Resource
    Electronic Resource
    Uptake and localization of99mTc-methylene diphosphonate in mouse osteosarcoma (1982)
    Springer
    European journal of nuclear medicine 7 (1982), S. 531-535 
    Details
    ISSN: 1619-7089
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The localization of99mTc-methylene diphosphonate (99mTc-MDP) in mouse osteosarcoma was studied using a skeletal scintigraphic method and macro- and microautoradiographic methods. On the skeletal scintigraph, the tumor showed a high uptake of99mTc-DMP and its concentration was about 20 times as high as the value seen in the muscular tissue. The macroautoradiography showed high activity in the tumor bone region and little activity in the nonossified region. On the microautoradiography, the activity of99mTc-MDP was localized in the mineralized matrix of tumor bone and was almost nil in the nonmineralized matrix (osteoid) and the tumor cells. These findings indicate that the mineralization of the tumor bone matrix plays an important role in99mTc-MDP uptake in osteosarcoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00571644
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    The repair process in experimentally induced avascular necrosis of the femoral head in dogs (1981)
    Springer
    Archives of orthopaedic and trauma surgery 99 (1981), S. 109-115 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Total necrosis of the femoral head was experimentally produced in dogs by freezing. The healing process was observed in a time sequence. There was a dense fibrous layer at the boundary between the necrotic bone mass and living bone tissue, in each dog which survived for 18 months after the surgery. The layers were similar to that commonly found in avascular necrosis of the femoral head in humans. Histological observation revealed that the establishment of the dense fibrous layer was the final result of three time dependent changes in biological potencies of granulation tissue, i.e., decreasing proliferating and differentiating potencies and increasing osteoclastic potency of mesenchymal cells within the granulation tissue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00389746
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  • 6
    Electronic Resource
    Electronic Resource
    Psoas transfer for the treatment of congenital dislocation of the hip (1979)
    Springer
    Archives of orthopaedic and trauma surgery 95 (1979), S. 159-165 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Seit 1965 wurde die anterolaterale Verpflanzung der Psoas-Sehne als eine routinemäßige chirurgische Behandlung bei angeborener Hüftluxation angewendet. Die Sehnenverpflanzung wurde zusammen mit einer offenen Einrenkung durchgeführt, wenn intrakapsuläre Repositionshindernisse auffallend sind. Pfannenverbessernde Verfahren oder Beseitigung der Fehlstellung des coxalen Femurendes wurden dabei nicht durchgeführt. An unserer Klinik wurden 87 Hüftgelenke mit dieser Methode in der Zeit von 1965 bis 1973 behandelt. Die Patienten (38 Hüfte) konnten nachuntersucht werden. Die durchschnittliche Beobachtungszeit beträgt 8 Jahre. Als Kontrolle wurden 13 Hüften, die offen eingerenkt waren, untersucht. Reposition des Femurkopfes und Entwicklung der Pfanne und des coxalen Femurendes wurden röntgenologisch nach dem Schema von Severin beurteilt. Es lag keine Reluxation vor. Das Ergebnis der offenen Einrenkung und der Psoas-Verpflanzung ist in 50% als I. oder II. Grad zu bezeichnen. Diese Erfolgsquote ist höher als die der Kontrolle, bei der 23% als I. oder II. Grad beurteilt wurden. Eine bessere Konzentrizität des Femurkopfes kann durch CE-Winkel (Wiberg) nachgewiesen werden. Es wurde festgestellt, daß die Pfannenentwicklung besser beeinflußt werden kann, wenn die Psoas-Verpflanzung bei Kindern unter 1 Jahr durchgeführt wurde. Die Pfannenentwicklung kann bei ä1teren Kindern wenig beschleunigt werden. Der detorquierende EMU dieser Psoas-Verpflanzung scheint fraglich zu sein, weil die Detorquierung der operierten Gruppe die der Kontrollgruppe nicht übersteigt.
    Notes: Summary Since 1965, anterolateral transfer of the psoas muscle has been employed by us as a routine surgical treatment for congenital dislocation of the hip joint. The transfer was carried out in association with open reduction in those patients in whom an intracapsular obstruction was evident, but corrective measures for acetabular dysplasia or cervicocapital deformity of the femur were not performed in this series. We treated 87 hip joints with this procedure from 1965 to 1973. In 38 hip joints, both open reduction and the psoas transfer were followed up for an average of 8 years. Thirteen hip joints with open reduction alone were included as controls. Position of the femoral head and development of the acetabulum and proximal end of the femur were assessed on X-rays, mainly after Severin's criteria. Redislocation was not encountered. Fifty percent of the hip joints with open reduction and the psoas transfer were classed as grade I or II. This figure is higher than that of controls, to which 23% were classed as grade I or II. Better concentricity of the head was achieved as determined by the CE angle (Wiberg). Development of acetabulum occurred when the transfer had been carried out in children under 1 year of age and was less likely in the older children. The detorsional effect of the psoas transfer remained questionable since detorsion in the transferred group did not exceed that of the controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00460113
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  • 7
    Electronic Resource
    Electronic Resource
    Elongation of brachymetatarsy with ceramic implant: A roentgenographic evaluation of its utility (1986)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 20 (1986), S. 1249-1256 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The metatarsal bone was elongated by intercalary implantation of a single-crystal alumina ceramic in 7 patients with brachymetatarsy. The implants were encased with new bone 24 months after surgery and resulted in 5.2 to 9.2 mm elongation of the metatarsal bone. The response of the bone to the ceramic implant was observed roentgenographically. No resorption or pseudoarthrosis of the bones, nor loosening or breakage of the implants, were observed. The alumina ceramic implant proved to be a useful substitute for a bone graft, because of its biocompatibility and strength.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820200813
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