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  • 1
    ISSN: 1573-868X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Coastal polynyas off East Queen Maud Land in Antarctica are examined using NOAA AVHRR infrared data. From image analyses, two locations of coastal polynyas in this region are identified; one in Breid Bay and the other along the shelf break. The areal coverage of the Breid Bay polynya is significantly related to the strength of katabatic winds, which maintain their strength over the coastal sea due to land topography favoring for their confluence, thereby being capable of removing newly formed ice. Land fast ice in the eastern part of the bay also plays an additional role in the formation mechanism. It is also found that the areal coverage of coastal polynyas in this region fluctuate coherently. Moreover, these fluctuations correspond to the synoptic index, which measures the strength of the offshore wind, with their peaks closely associated with the areal peaks. These facts strongly suggest the influence of synoptic scale weather on the formation and maintenance of polynyas in this region.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1433-0350
    Keywords: Key words Operative approach ; Orbitotomy ; Hypothalamus ; Craniopharyngioma ; Pituitary adenoma ; Radiosurgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although several approaches to the hypothalamus have been used, none is able to give full views of the hypothalamus. The risk of permanent morbidity for hypothalamo-pituitary functions is still high, especially in patients with cranio-pharyngioma. Basal interhemispheric supra-chiasmal or infra-chiasmal approaches via superomedial orbitotomy were developed for better visualization of the hypothalamus. Operative techniques and results, including combination treatment with radiosurgery, are reported. Twelve patients with tumors compressing the hypothalamus upward or extending into the III ventricle, or both, were operated on: 3 tumors were removed totally, 6 tumors subtotally and 3 tumors partially. Six patients received radiosurgery for residual tumor. Four patients with hypopituitarism preoperatively required oral corticosteroids and thyroid hormones postoperatively. The basal interhemispheric approach via superomedial orbitotomy is useful for better visualization of the hypothalamus and preservation of hypothalamo-pituitary functions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-7373
    Keywords: glioblastoma multiforme ; radiation therapy ; large dose fraction irradiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-four adults with glioblastoma multiforme (astrocytoma, grade 4) underwent postoperative large dose fraction radiotherapy (LDFR; 5 Gy twice weekly) with Linac X-rays. The outcome in this group was compared with that of 26 patients who received conventional fractionated radiotherapy (CFR; 2 Gy 5 times weekly). The time, dose, and fractionation (TDF) factor was about 100 in both groups. The survival rates following LDFR and CFR were, respectively, 63% vs 65% at 1 year; 36% vs 8% at 2 years; 17% vs 4% at 3 years; and 4% vs 0% at 5 years. Although the survival curve for LDFR was superior to that for CFR, the difference was not statistically significant. Autopsies of nine LDFR and 13 CFR patients showed no residual tumor in one case and no cases, respectively; small residual tumor in three cases in each group; extensive coagulation necrosis of the tumor and surrounding brain tissue in one LDFR and four CFR patients; tumor proliferation in three LDFR and four CFR cases; and mixed glioblastoma and fibrosarcoma in one LDFR and two CFR patients. These results suggest that maximum tumor removal followed by LDFR may offer a better prognosis for patients with glioblastoma than that offered by surgery plus CFR.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Medical molecular morphology 27 (1994), S. 1-7 
    ISSN: 1860-1499
    Keywords: Medulloblastoma ; Primitive glioma ; Differentiation ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To increase our understanding of the differentiation potential and cytogenesis of embryonal tumors in the brain, 12 medulloblastomas and 10 primitive gliomas were studied by electron microscopy. Of the medulloblastomas, 6 cases were undifferentiated tumors that demonstrated fine processes similar to microspikes. The remaining 6 cases were poorly-differentiated tumors. Axon-like processes were seen in 4 of these cases, including one with dense core vesicles. Astroglial processes were seen in 4 cases. Of the primitive gliomas, there were 2 undifferentiated tumors and 8 poorly-differentiated tumors. Some of the undifferentiated tumor cells had broad cytoplasmic processes. Of the 8 poorly-differentiated gliomas, there were groupings of junctional complexes in 7, microvilli in 4 and bundles of intermediate filaments in 5. It is concluded that medulloblastomas have both neuronal and glial differentiation potentials and that primitive gliomas have only glial differentiation potential. The origin of medulloblastomas may be from the remnants of cell nests with a multipotential differentiation capacity, and the origin for primitive gliomas may be from remnants of glial precursor cells.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Medical molecular morphology 28 (1995), S. 111-117 
    ISSN: 1860-1499
    Keywords: Atypical meningioma ; Anaplastic meningioma ; Ultrastructure ; Brain invasion ; Recurrence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To clarify the cytologic features of atypical and anaplastic meningiomas, 11 tumors from 4 patients were examined by electron microscopy and compared to 10 classic meningiomas. Although all of the classic meningiomas had oval nuclei, many cytoplasmic organelles, typical regular interdigitation of cell processes, and many well-developed desmosomes with many intermediate filaments, atypical meningiomas showed irregularlyindented nuclei, poorly-developed interdigitation of irregular cell processes, and a decreased number of desmosomes. Anaplastic meningiomas were composed of immature cells with scant cytoplasm and poorly-developed cell processes. Mitoses were occasionally observed. The intercellular spaces were obvious, and immature desmosomes with small amounts of filaments were rarely found. A high recurrence rate and metastases can be predicted from the presence of loose contacts between tumor cells and frequent mitoses in atypical and anaplastic meningiomas.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Medical molecular morphology 29 (1996), S. 129-136 
    ISSN: 1860-1499
    Keywords: Brain tumor ; Fibromyxoma-like tumor ; Sella turcica
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An intra- and supra-sellar tumor in a 22-year-old woman was studied. Histologically, this tumor was composed of spindle-shaped cells with oval nuclei. The tumor cells were dispersed in a myxomatous, eosinophilic ground substance reacting positively to alcian blue. Cellular processes formed a mesh structure. Immunohistochemically, the tumor cells showed a positive reaction against vimentin. Ultrastructurally, spindle-shaped tumor cells contained indented oval nuclei, and abundant cytoplasm with many intermediate filaments and many cisternae of the rough endoplasmic reticulum. Cilia were rarely observed. The pathological diagnosis was fibromyxoma-like tumor.
    Type of Medium: Electronic Resource
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