Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Vimentin expression of renal cell carcinoma in relation to DNA content and histological grading: a combined light microscopic, immunocytochemical and cytophotometrical analysis (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 18 (1991), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An immunocytochemical and cytophotometrical analysis of 30 renal cell carcinomas was carried out in order to investigate the expression of cytokeratin and vimentin in relation to the ploidy and mitotic index. Thirty renal cell carcinomas were studied using monoclonal antibodies CAM 5.2 and anti-vimentin in a biotin-streptavidin staining procedure. The renal cell carcinomas were classified according to the criteria of Furhman with a nuclear grading from I to IV. All carcinomas expressed cytokeratin, whereas co-expression with vimentin was present only in 53%. Expression for both intermediate filaments was present in aneuploid tumours with a marked nuclear pleomorphism and was more frequently related to a tubulo-papillary and pseudosarcomatous growth pattern. It is suggested that vimentin expression in renal cell carcinomas may be useful as a prognostic index in addition to nuclear grade, DNA content, mitotic rate and tumour stage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1991.tb00852.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Early adjuvant Adriamycin in superficial bladder carcinoma (1983)
    Springer
    Cancer chemotherapy and pharmacology 11 (1983), S. S32 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A multicenter study was performed in 110 patients with superficial transitional cell carcinoma of the bladder. Adriamycin (50 mg/50 ml) was administered intravesically within 24 h after transurethral resection of TA-T1 (O-A) bladder tumors. Instillation was repeated twice during the first week, then weely during the first month and afterwards monthly for 1 year. The tolerance was evaluated in these 110 patients, and 29 patients presented with local side-effects. In 24 of these patients chemical cystitis was severe enough for them to drop out of the study. No systemic side-effects were observed. Recurrence was studied in 82 evaluable patients after 1 year of follow-up and in 72 patients followed for 2–3 years (mean 32 months). Of the 82 patients studied after 1 year, 23 had primary and 59 recurrent disease. Of the 82 evaluable patients, 50 did not show any recurrence after 1 year (61%), while 32 presented with one or more recurrence (39%). Of these recurrences, 27 were T1 tumors while five progressed to more highly invasive lesions. In patients that were free of recurrence during the first year, 80% remained tumor-free during the 2- to 3-year follow-up period. Of the patients developing one or more recurrences during the first year, only 50% presented with further recurrence once the instillations were stopped. The beneficial effect of Adrimacin appears obvious and might be related to the drug itself, the early and repeated instillations after TUR, or both.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256714
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Patient Satisfaction and Complications Following Sacral Nerve Stimulation for Urinary Retention, Urge Incontinence and Perineal Pain: a Multicenter Evaluation (2000)
    Springer
    International urogynecology journal 11 (2000), S. 231-236 
    Details
    ISSN: 1433-3023
    Keywords: Key words:Incontinence – Neuromodulation – Neurostimulation – Pain – Retention – Voiding dysfunction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The aim of the study was to determine the success rate, the complications, the failures and the solutions found in troublesome cases. A retrospective study was performed in three university centers in Belgium. Between March 1994 and April 1998, a quadripolar electrode and a pulse generator were implanted in 53 patients (8 men, 45 women, 43 ± 12 years, mean follow-up 24 ± 8 months, range 13–39 months). During the first few months, 45 (85%) of the 53 patients had an objective response. Eight late failures occurred, with a mean failure delay of 9 ± 5 months. We performed 15 revisions in 12 patients. Major complications were pain and current-related troubles. The outcome was significantly better (P= 0.001) in post-stress incontinence surgery patients. Device-related pain was found more frequently in patients with dysuria and/or retention or perineal pain, and the test stimulation was less reliable (P= 0.025) in patients with a psychiatric history. Sacral nerve stimulation is efficient in treating patients with refractory lower urinary tract symptoms and/or perineal pain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001920070031
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Urinary excretion of tubular proteins and the technetium-99m dimercaptosuccinic acid (DMSA) absolute renal uptake in partial ureteral obstruction in rats: a functional evaluation of hydronephrotic kidneys (1999)
    Springer
    Urological research 27 (1999), S. 127-133 
    Details
    ISSN: 1434-0879
    Keywords: Key words Ureteral obstruction ; Proteinuria ; Tubular proteins ; Hydronephrosis ; DMSA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this longitudinal study was to evaluate tubular proteinuria in rats with unilateral (UPO) and bilateral (BPO) partial ureteral obstruction with the dimercaptosuccinic acid (DMSA) scan as the gold standard for measuring renal tubular damage. We studied 70 female Wistar rats: 28 animals with UPO, 28 animals with BPO, 7 sham-operated animals, and 7 controls. All animals with obstructed ureters showed renal dilatation on the diethylenetriaminepentaacetic acid DTPA images 1 and 5 weeks postoperatively. One week following UPO and BPO, tubular proteinuria and urinary N-acetyl-beta-d-glucosaminidase (NAG) activity increased (P 〈 0.01) and the absolute DMSA uptake decreased (P 〈 0.01). Persistently (week 6) high tubular proteinuria was found in 29% of the animals and was related to severe damage on the DMSA scan (P 〈 0.01) and to albuminuria (P 〈 0.05). Renal tubular damage was demonstrated by measuring renal enzymes, tubular proteins, and DMSA uptake after UPO and BPO. Persistent elevated tubular proteinuria was related to severely damaged kidneys.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002400050098
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Low-voltage coagulation for welding sutures watertight: an experimental study (1992)
    Springer
    Urological research 20 (1992), S. 425-427 
    Details
    ISSN: 1434-0879
    Keywords: Welding ; Watertight ; Suture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A rat model was developed to test the watertightness of sutures. In this model it was proved that welding by use of low-voltage coagulation current did not improve on the watertightness obtained with conventional skin suturing. The mean leak pressure after welding was about 4.2 cm H2O, i.e. statistically significantly lower than the mean leak pressure of the conventional suture, which is 14.1 cm H2O. Neither addition of protein solder nor an additional conventional suture improved these results. It is therefore concluded that low-voltage coagulation is unsuitable for welding tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294500
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Early adjuvant adriamycin in superficial bladder carcinoma (1983)
    Springer
    World journal of urology 1 (1983), S. 86-88 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A multicenter study was performed in 110 patients with superficial transitional cell carcinoma of the bladder. Adriamycin (50 mg/50 ml) was administered intravesically within 24 h after transurethral resection of TA-T1 (O-A) bladder tumors. Instillation was repeated twice during the first week, then weekly during the first month, and monthly for 1 year. Tolerance was evaluated in these 110 patients and 29 patients presented with local side effects. In 24 of these patients the chemical cystitis was severe enough to cause them to drop out of the study. No systemic side effect was observed. Recurrence was studied in 82 evaluable patients at 1 year of follow-up and on 72 patients followed for 2–3 years (mean: 32 months). Of these 82 patients, 23 were primary cases and 59 recurrent. In all 82 patients, 50 (61%) did not show any recurrence after 1 year, while 32 (39%) presented with one or more recurrences. Of these recurrences, 27 were T1 tumors while 5 progressed to more invasive lesions. In patients that were free of recurrence during the first year, 80% remained tumor-free during the 2–3 year follow-up period. In patients who had developed one or more recurrences during the first year, only half of them developed further recurrences once the instillations were stopped. The beneficial effect of adriamycin appears obvious and might be related to the drug itself, the early and repeated instillations after TUR, or both factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326749
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Elevated tubular proteinuria, albuminuria and decreased urinary N-acetyl-β-D-glucosaminidase activity following unilateral total ureteral obstruction in rats (1998)
    Springer
    Urological research 26 (1998), S. 285-289 
    Details
    ISSN: 1434-0879
    Keywords: Key words Ureteral obstruction ; Proteinuria ; Hydronephrosis ; Glucosaminidase ; Tubular proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Urinary tubular proteinuria and N-acetyl-β-d-glucosaminidase (NAG) activity has not yet been studied after unilateral total ureteral obstruction (UTO). The aim of the study was (1) to evaluate in a longitudinal study (7 weeks) the behaviour and the potential clinical value of tubular proteinuria and urinary NAG activity after UTO; (2) to study the physiopathology of the non-obstructed contralateral kidney by using these two different markers of tubular damage. Methods: in 28 female, adult Wistar rats (UTO: n= 16, sham: n= 12), tubular proteinuria and urinary NAG activity were measured before and 1 and 5 weeks after surgery. Results: a significant (P 〈 0.01) increase in tubular proteinuria/creatinine ratio and urinary creatinine and a decrease in urinary NAG activity was found 1 week after UTO. All parameters normalized after 6 weeks. Albuminuria increased progressively (P 〈 0.01) during the study. Conclusion: tubular proteinuria increases during the first week following UTO in rats. The initial increase of low molecular weight proteins following UTO is not due to tubular damage as no parallel increase of urinary NAG was found. We suggest an initial tubular overperfusion with primary urine, due to an increased single nephron glomerular filtration and overruling the reabsorption capacity of the proximal tubules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002400050059
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Rationale for local toxicity of calcium chelators (1992)
    Springer
    Urological research 20 (1992), S. 19-21 
    Details
    ISSN: 1434-0879
    Keywords: Calcium oxalate ; Renal lithiasis ; Chemolysis ; Ethylenediaminetetraacetate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Calcium chelating agents, such as ethylenediaminetetraacetate are toxic to urothelium. Their capacity to form complexes with calcium ions, which is the basis for their chemolytical effectiveness, also determines their toxicity. A decrease of chemolytical effectiveness by prior saturation of the chelator with Ca2+ or by lowering the pH to levels unfavourable for calcium binding significantly diminishes tissue injury. Exchange of Mg2+ ions does not, however, diminish tissue damage. The clinical use of calcium ligands is therefore unsafe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294329
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Toxicity of litholytic ethylenediaminetetraacetic acid solutions to the urothelium of the rat and dog (1991)
    Springer
    Urological research 19 (1991), S. 265-268 
    Details
    ISSN: 1434-0879
    Keywords: Renal lithiasis ; Chemolysis ; Ethylenediaminetetraacetic acid (EDTA)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The toxicity to the urothelium of bipotassium ethylene-diaminetetraacetic acid (K2-EDTA) buffered with 0.2 M triethanolamine (TEA) at pH 8 and 8.5 was tested in rats and dogs. Even at a low concentration of 3.125 mM, K2-EDTA is very noxious to the bladder mucosa. This toxicity is not due to the buffer TEA, which is well tolerated. Although buffered K2-EDTA, at pH 8.5 is an excellent chemolytic agent for calcium-containing stones, its clinical use is limited by this toxicity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00305309
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Effect of sludge ice cooling on renal function and renal histology in the dog (1981)
    Springer
    Urological research 9 (1981), S. 111-114 
    Details
    ISSN: 1434-0879
    Keywords: Renal hypothermia ; Intrarenal surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of sludge ice surface cooling on the compensatory hypertrophied dog kidney was investigated. Renal function was measured prior to and on days 1, 3 and 7 after the cooling procedure by means of inulin clearance, PAH clearance and sodium excretion capacity during normal hydration and after volume expansion. No alteration in renal function was shown. No freezing lesions or thromboses were seen on histological examination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00254404
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...