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  • 1
    Electronic Resource
    Electronic Resource
    Hypericin, the Photodynamic Pigment from St. John'swort (1941)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 63 (1941), S. 2570-2574 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01855a009
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The information requested by patients prior to giving consent to anaesthesia (2003)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 58 (2003), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Patients in a teaching hospital in Scotland were given the opportunity to ask for further information relating to their peri-operative anaesthetic management. One investigator visited all of the patients pre-operatively and asked a standard list of anaesthetic-related questions. Our objectives were to determine what additional information patients would request before giving their consent to anaesthesia. The majority of patients (n=469, 67%) had no further questions at a point when so-called consent could have been obtained. Of the questions asked, 209 (66%) were related to anaesthesia and 93 (30%) to the proposed surgery. Only two patients in the group studied requested a full explanation of their peri-operative anaesthetic management. The question most commonly asked related to the duration of surgery, with less priority being given to questions relating to complications of anaesthesia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2003.03189_5.x
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  • 3
    Electronic Resource
    Electronic Resource
    Hypoxic pulmonary vasoconstriction and the pharmacologically denervated lung (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 37 (1982), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The roles of the autonomic nervous system and cardiac output on hypoxic pulmonary vasoconstriction were studied in 15 mongrel dogs anaesthetised with intravenous pentoharbitone (30 mg/kg) and the lungs mechanically ventilated to maintain normal arterial blood gases. After a hypoxic challenge in Group I (n =6) and Group II (n =3) animals, autonomic denervation was achieved by total spinal block with tetracaine (20 mg) injected into the cisterna magna. Group I animals received a large volume of intravenous fluid (80 ml/kg normal saline) before the block while Group II animals were given minimum fluid. When Group I animals were exposed to 10% inspired oxygen, mean pulmonary arterial pressure increased by 88 and by 72% before and after the block, respectively. The cardiac output increased by 27% with hypoxia before the block while it did not change significantly with hypoxia after the block. The pulmonary vascular resistance increased by 65 and by 152% with hypoxia before and after the block. Group II animals were also exposed to 10% inspired oxygen. They showed a similar response to Group I animals before the block. However, after the block irreversible hypotension developed with hypoxia. In Group III animals (n =6), the same anaesthesia and hypoxic challenge protocol was used. Immediately after measurements at 10 minutes of hypoxia, the inferior vena cava was constricted to reduce the cardiac output to the control level and another set of measurements were made. The cardiac output increased by 30% with hypoxia and then was reduced to the control level with vena caval constriction. The mean pulmonary arterial pressure increased by 125% with hypoxia and then it decreased slightly with the inferior vena cava constriction. The pulmonary vascular resistance increased by 95% with hypoxia and then it further increased by 28% with the vena caval constriction. These results suggest that sympathectomy accentuates rather than attenuates the hypoxic pulmonary vasoconstriction and that an increase in cardiac output counteracts hypoxic pulmonary vasoconstriction. The results also suggest that adequate intravascular volume and oxygenation are extremely important for maintaining homeostasis when reflex sympathetic stimulation to the cardiovascular system has been eliminated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1982.tb01056.x
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  • 4
    Electronic Resource
    Electronic Resource
    Review of ethics in paediatric anaesthesia: consent issues (2001)
    Oxford UK : Blackwell Science Ltd
    Pediatric anesthesia 11 (2001), S. 0 
    Details
    ISSN: 1460-9592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The concepts of law and ethics as related to medical practice have always been of paramount importance to the medical profession. This series of three reviews, examines the changes in the law in the last 10 years in relation to ethics and the practice of paediatric anaesthesia. The reviews cover, in a practical question and answer format, the topics of consent, research, intensive care and organ donation issues in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9592.2001.00699.x
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  • 5
    Electronic Resource
    Electronic Resource
    Review of ethics in paediatric anaesthesia: intensive care issues (2001)
    Oxford UK : Blackwell Science Ltd
    Pediatric anesthesia 11 (2001), S. 0 
    Details
    ISSN: 1460-9592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This is the third of a series of three articles examining the recent changes in the law in relation to ethics and the practice of paediatric anaesthesia. The review covers, in a practical question and answer format, the topics of consent, research, intensive care issues and organ donation in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9592.2001.00701.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Review of ethics in paediatric anaesthesia: research issues (2001)
    Oxford UK : Blackwell Science Ltd
    Pediatric anesthesia 11 (2001), S. 0 
    Details
    ISSN: 1460-9592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This is the second of a series of three articles reviewing the recent changes in the law in relation to ethics and the practice of paediatric anaesthesia. The review covers, in a practical question and answer format, the topics of consent, research, intensive care issues and organ donation in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-9592.2001.00700.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Legal and ethical considerations of research in children: implications for anaesthetists (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Pediatric anesthesia 2 (1992), S. 0 
    Details
    ISSN: 1460-9592
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Undertaking research in children creates many legal and ethical dilemmas and it is essential that paediatric anaesthetists fully understand the complex issues raised. Most commentators agree that therapeutic research is justified. The question of non-therapeutic research, however, is much more controversial, with widespread disagreement about its ethical justification. The extreme arguments advocating no research at all or justifying it as a duty to society are not acceptable. The middle of the road attitude of balancing the risks to the child with the many advantages to society as a whole should prevail. If risks are significant, research should not be allowed. The law itself appears to offer no statutory guidelines which, therefore, should be implemented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9592.1992.tb00475.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Microbial Ecology and Evolution: A Ribosomal RNA Approach (1986)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Microbiology 40 (1986), S. 337-365 
    Details
    ISSN: 0066-4227
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.mi.40.100186.002005
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Nucleotide sequence of Bacillus megaterium 5 S RNA
    Amsterdam : Elsevier
    FEBS Letters 44 (1974), S. 322-323 
    Details
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(74)81168-3
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    The intracellular distribution of metal ions in rat liver
    Amsterdam : Elsevier
    Experimental Cell Research 11 (1956), S. 362-367 
    Details
    ISSN: 0014-4827
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0014-4827(56)90112-4
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    Paper (German National Licenses)
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