ISSN:
1432-1084
Keywords:
Liver, interventional procedures
;
Lasers
;
Liver, US studies
;
Liver neoplasms, therapy
;
Hyperthermia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The present report evaluates the efficacy and safety of percutaneous interstitial laser tissue ablation of the liver in nine New Zealand rabbits. A Nd: YAG laser was coupled to a quartz fibreoptic guide (600 μm) with a flat tip. The fibre and a thermocouple were placed in the lumen of two Chiba needles (18G) and these were inserted into the liver 10 mm apart under ultrasound guidance. The laser was fired for 5 min at 1, 3 and 5 W power, respectively, in three groups of rabbits. There were no acute complications and all the rabbits except one survived until the established time of sacrifice. The procedure induced a cavity surrounded by a zone (about 10 mm) of coagulative necrosis. After 2 weeks a strong peripheral inflammatory response was evident and after 4 weeks a capsule of connective tissue enclosed the lesions. Our study seems to offer a safe and rapid technique producing a “guaranteed kill radius” for the treatment of small hepatic neoplasms.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00173518
Permalink
