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  • 1
    Electronic Resource
    Electronic Resource
    The thermal conductivity of defective crystals (1997)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 106 (1997), S. 3681-3687 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We have calculated the thermal conductivity of pure KCl and KCl doped with RbCl using the Green–Kubo theory and classical molecular dynamics. Both shell-model and rigid-ion potentials are employed to describe the ionic interactions, and we find that the inclusion of ionic polarisability significantly changes the calculated conductivity at a given temperature. We find fairly good agreement between the simulation results and the available experimental data for both pure and doped systems. The shell model provided a slightly better description than the rigid-ion potential, although neither proved to be entirely satisfactory over the temperature range investigated (300–900 K). The relative merits of the potentials are discussed in the light of these results, as are the technical issues raised by the calculations. These studies demonstrate the capacity of the approach to yield quantitative predictions of the transport properties of ionic materials using shell-model potentials. This will be of use in treating systems for which rigid-ion models are inadequate. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.473462
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  • 2
    Electronic Resource
    Electronic Resource
    Myocardial metabolism studied during warm blood antero-retrograde reperfusion in ischaemic human hearts (1998)
    Springer
    Acta diabetologica 35 (1998), S. 67-73 
    Details
    ISSN: 1432-5233
    Keywords: Key words Warm blood reperfusion ; Energy metabolism ; Myocardial ischaemia ; Coronary artery bypass ; Heart arrest ; Myocardial reperfusion injury
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We propose modified warm blood antegrade-retrograde reperfusion (WBARR) of arrested hearts as a metabolic model with which to study substrate exchange and energy metabolism during the recovery phase after 90 min of ischaemia in man. Eleven anaesthetized patients undergoing aorto-coronary bypass were studied during WBARR. The protocol was designed as follows: period 1, a warm blood reperfusion with potassium (3 min); period 2, a warm blood reperfusion without potassium (2 min). The perfusion flow rate averaged 250±2 ml/min at the beginning of period 1 and 218±19 ml/min at the beginning and at the end of period 2; the perfusion was performed antegradely and retrogradely in the arrested hearts. Samples were simultaneously taken from the coronary venous sinus (CVS) and from the aortic root needle (AR). At the beginning of WBARR lactate release was 85±44 μmol/min and at the end it had significantly decreased to 21±99 μmol/min (P〈0.03). Simultaneously, non-esterified fatty acids (NEFA) and β-hydroxy-butyrate were initially released (71±61 and 22±66 μmol/min, respectively), while at the end of the WBARR there was an uptake of both NEFA (20±22 μmol/min; P〈0.01) and β-hydroxy-butyrate (12±35 μmol/min; P=0.290). Alanine, glycerol and branched chain amino acid balance across the heart did not significantly change. In summary after 90 min of ischaemia the heart energy metabolism is mainly anaerobic and based on glucose consumption, with lactate, NEFA and amino acids, which are mainly released. After 5 min of WBARR (recovery from ischaemia), lactate release is significantly reduced and NEFA becomes the energy supply of the heart. In conclusion, (1) WBARR is a valuable method with which to study myocardial metabolism in anaesthetized humans and may be combined with the use of tracers; (2) the study of myocardial metabolism in arrested hearts eliminates the imprecisions arising from the non-continuous coronary blood flow; (3) NEFA become an important source of energy utilized by human hearts in the recovery phase from ischaemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005920050105
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  • 3
    Electronic Resource
    Electronic Resource
    Results of surgical treatment of arthrofibrosis after ACL reconstruction (1995)
    Springer
    Knee surgery, sports traumatology, arthroscopy 3 (1995), S. 83-88 
    Details
    ISSN: 1433-7347
    Keywords: ACL reconstruction ; Arthrofibrosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Sports Science
    Notes: Abstract We prospectively studied 31 knee arthrolyses performed for loss of motion after intra-articular anterior cruciate ligament (ACL) reconstruction. The arthrolysis was performed on average 10.6 months after the reconstruction (range 4–25). Seven knees were localized forms. They were treated with arthroscopic removal of a fibrous nodule and scar tissue anterior to the ACL, which was preserved. Twenty-four knees were global forms and treated arthroscopically (14) or in open procedure (10). Suprapatellar, medial, and lateral gutter adhesions were sectioned, and fibrous tissue was removed from the anterior compartment. A posteromedial and/or posterolateral capsulotomy was necessary in 7 knees. The ACL graft was nonfunctional and/or malpositioned in 19 knees. The results were evaluated with the IKDC form with an average follow-up of 3.5 years (range 1.5–7). Preoperatively the localized forms had an average extension loss of 11° and an average flexion loss of 14° compared to the opposite knee. At follow-up all the knees were satisfactory for symptoms. All except one achieved a satisfactory motion (within 5° of extension loss and 15° of flexion loss) and a satisfactory final result. Global forms had a greater preoperative flexion loss (average 34°) and extension loss (average 17°). At follow-up 58% were satisfactory for symptoms and 71% for arc of motion. However, the final result was satisfactory in only 37%. In conclusion, local forms have a good prognosis. In global forms motion may be improved by surgery, but the final result is downgraded by symptoms. Arthrolyses performed within 8 months from index operation had a better outcome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01552380
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  • 4
    Electronic Resource
    Electronic Resource
    Presurgical identification of hibernating myocardium by combined use of technetium-99m hexakis 2-methoxyisobutylisonitrile single photon emission tomography and fluorine-18 fluoro-2-deoxy-d-glucose positron emission tomography in patients with coronary artery disease (1992)
    Springer
    European journal of nuclear medicine 19 (1992), S. 874-881 
    Details
    ISSN: 1619-7089
    Keywords: Myocardial perfusion ; Myocardial metabolism ; Radionuclide imaging ; Myocardial viability ; Coronary artery bypass grafting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We tested the possibility of identifying areas of hibernating myocardium by the combined assessment of perfusion and metabolism using single photon emission tomography (SPET) with technetium-99m hexakis 2-methoxyisobutylisonitrile (99mTc-MIBI) and positron emission tomography (PET) with fluorine-18 fluoro-2-deoxy-d-glucose (18F-FDG). Segmental wall motion, perfusion and 18F-FDG uptake were scored in 5 segments in 14 patients with coronary artery disease (CAD), for a total number of 70 segments. Each subject underwent the following studies prior to and following coronary arterybypass grafting (CABG): first-pass radionuclide angiography, electrocardiography gated planar perfusion scintigraphy and SPET perfusion scintigraphy with 99mTc-MIBI and, after 16 h fasting, 18F-FDG/PET metabolic scintigraphy. Wall motion impairment was either decreased or completely reversed by CABG in 95% of the asynergic segments which exhibited 18F-FDG uptake, whereas it was unmodified in 80% of the asynergic segments with no 18-FDG uptake. A stepwise multiple logistic analysis was carried out on the asynergic segments to estimate the postoperative probability of wall motion improvement on the basis of the preoperative regional perfusion and metabolic scores. The segments with the highest probability (96%) of functional recovery from preoperative asynergy after revascularization were those with a marked 18F-FDG uptake prior to CABG. High probabilities of functional recovery were also estimated for the segments presenting with moderate and low 18F-FDG uptake (92% and 79%, respectively). A low probability of functional recovery (13 %) was estimated in the segments with no 18F-FDG uptake. Despite the potential limitations due to the semiquantitative analysis of the images, the method appears to provide reliable information for the diagnostic and prognostic evaluation of patients with CAD undergoing CABG and confirms that the identification of hibernating myocardium with 18F-FDG is of paramount importance in the diagnosis of patients undergoing CABG.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00168164
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