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  • 1
    Electronic Resource
    Electronic Resource
    SPATIAL CHARACTERISTICS OF TURBULENCE IN THE AORTA (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 404 (1983), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1983.tb19501.x
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  • 2
    Electronic Resource
    Electronic Resource
    A model for flow through discontinuities in the tight junction of the endothelial intercellular cleft (1994)
    Springer
    Bulletin of mathematical biology 56 (1994), S. 723-741 
    Details
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract A mathematical model for steady flow through a discontinuity in the tight junction of an endothelial intercellular cleft is presented. Subject to plausible assumptions the problem of calculating the flow in the cleft, in either the presence or the absence of a fibre matrix, reduces to the solution of Laplace's equation in a two-dimensional domain. For an idealized geometry representing a discontinuity between two semi-infinite tight junction regions, a general analytic solution is found by means of conformal mappings. The model geometry, unlike those assumed in previous studies, allows the tight junction regions to be out of alignment with each other, and even to overlap, modelling flow through a tortuous, rather than a direct, pathway. Useful asymptotic approximations for the flow rate are derived when the discontinuity is either very small or very large. For small discontinuities, the predicted flow rate is much greater than a naïve estimate based on uniform parallel flow through the discontinuity. For the special case where the tight junction regions are aligned with each other, comparison of our results with those of an approximate treatment due to Tsayet al. [Chem. Engng Commun. 82, 67–102 (1989)] shows generally very close agreement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02460718
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  • 3
    Electronic Resource
    Electronic Resource
    Measurements of oxygenation and perfusion in skeletal muscle using multiple microelectrodes (1997)
    Springer
    Journal of muscle research and cell motility 18 (1997), S. 149-159 
    Details
    ISSN: 1573-2657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract This paper describes an apparatus to measure tissue oxygenation and perfusion (as measured by the wash-in rate of gaseous hydrogen) simultaneously at multiple points in muscle using needle microelectrodes. The development of suitable electrodes and apparatus is described, as well as the development of the method and its validation. In particular, the potential for tissue damage secondary to electrode insertion, the need for in vivo voltammetric determination of the operating potential and the extent of any electrode-tissue and of electrode--electrode interactions are explored, and are shown to be insufficient in magnitude to affect the technique. Its subsequent use to characterise oxygenation and perfusion in rabbit skeletal muscle at rest is also described. In resting tibialis anterior muscle of the rabbit the mean pO2 was 18 ± 13.3 mm Hg and the mean perfusion was 4.4 ± 1.3 ml s−1 100 g−1. There was a heterogeneity in simultaneously-measured values of pO2 and perfusion at different points within muscle, and also a temporal variation at the same site. The spans between the highest and lowest simultaneously-measured values of pO2 in muscle ranged from 14 to 80 mm Hg, and for perfusion, from 1 to 12 ml s−1 g−1. No significant correlation was evident from histological examination between either pO2 or perfusion and surrounding fibre type or capillary density
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018653521686
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  • 4
    Electronic Resource
    Electronic Resource
    Simulation of nonstationary spectral analysis of turbulence in the aorta using a modified autoregressive or maximum entropy (AR/ME) method (1987)
    Springer
    Medical & biological engineering & computing 25 (1987), S. 533-542 
    Details
    ISSN: 1741-0444
    Keywords: Autoregressive spectrum analysis ; Ensemble average ; Maximum entropy method ; Nonstationary stochastic process ; Spectral analysis ; Turbulence in the aorta
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract A new method of parametric spectral calculation based on the ensemble average technique, which is a natural expansion of the Burg's maximum entropy method, is proposed. This method is applied to a set of numerical simulation data which simulate turbulent velocity fluctuations data measured in the canine aorta with a hot-film anemometer. The autoregressive order of the spectral calculation is chosen by the minimum AIC (Akaike's information criteria) method. It is shown that the proposed method used with the minimum AIC method has a very good performance calculating smooth averaged spectra in the short-time quasisteady spectral analysis of nonstationary processes such as turbulence in the aorta.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02441746
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  • 5
    Electronic Resource
    Electronic Resource
    Influence of solvent composition on the mechanical properties of arterial elastin (1990)
    New York : Wiley-Blackwell
    Biopolymers 29 (1990), S. 729-735 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: We have investigated the effects of changes in solution composition on the mechanical properties of rings of arterial elastin. The time course of force equilibration at constant strain following a change in the composition of the bathing solution was measured. Both the force developed during slow extension and force relaxation following rapid straining were also measured in each of the test solutions. The results are difficult to summarize because all of the primitive quantities measured - sample dimension, slope of the force-extension curve, force overshoot and time of relaxation - as well as the derived quantities such as elastic modulus changed in different and apparently uncorrelated ways. Changes in pH and ionic composition of the bathing solution had small effects consistent with the low fixed charge density of elastin. Solutions of glucose, sucrose, and ethylene glycol had larger effects consistent with changes in hydrophobic interactions. The viscosity of the solution that penetrated the intrafibrillar space of the elastin appeared to be a major determinant of the dynamic response.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bip.360290407
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    Paper (German National Licenses)
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