ISSN:
1573-6881
Keywords:
Protein turnover
;
interconvertible enzymes
;
protein degradation and phosphorylation state
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
,
Physics
Notes:
Abstract Steady-state and kinetic equations have been developed which characterize the rates of formation, interconversion, and degradation of an enzyme protein subject to reversible phosphorylation. The theoretical model system incorporates separate fractional degradative rate constants for the phosphorylated and dephosphorylated protein species. The classical models for interconvertible enzymes, and for protein turnover, are special limiting situations of the general model presented here.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00743237
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