ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary 1. Under the action of deuterophosphoric acid the dienone (VIII) cyclizes to the monodeutero-cyclopentenone (IXa) which, an ozonization, gives the deutero-ketoacid (X); oxidation of the latter with bromide lye leads to the detero-dicarboxylic acid (XI). 2. The dienone (VIII) and the cyclic ketone (IX) practically do not exchange their hydrogens for deuterium in the conditions of cyclization and, consequently, the entry of deuterium into the molecule of the cyclic ketone only takes place in the instant of its cyclization. 3. The results obtained are convincing evidence of the correctness of the proposed ionic mechanism of this cyclization reaction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01170117
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