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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science, Ltd
    Clinical and experimental pharmacology and physiology 32 (2005), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Resistance changes of the afferent and efferent arterioles determine blood flow and filtration rate in the kidney. The tone of both vessels results from the influence of nerves and humoral and paracrine factors, through a balance of constrictor and dilator systems. Angiotensin (Ang) II and nitric oxide (NO) are important factors determining vascular tone.2. In the present review, we show that, in addition to the basal production of NO, a specific and significant AngII-induced release of NO occurs in glomerular arterioles. Data from investigations of arteriolar contraction, as well as from fluorescence measurements of NO, in the presence of selective angiotensin AT1 and AT2 receptor antagonists indicate an AT1 receptor-stimulated release of NO in afferent arterioles.3. The AngII-induced liberation of NO could prevent glomerular arterioles from a marked constriction, particularly in situations of high AngII levels in the kidney.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 83 (2000), S. 388-394 
    ISSN: 1439-6327
    Keywords: Key words Exercise ; Heart rate variability ; Respiration ; Cardiorespiratory interaction ; Hilbert transformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to analyze the dynamic behavior of the high-frequency component (HF 〉 0.15 Hz) of heart rate variability (HRV) and the respiratory frequency in relation to the anaerobic threshold (AT). Twenty-two healthy subjects [mean (SD) age: 24 (6) years, height: 175 (10) cm, body mass: 65 (11) kg] completed a ramp load, with increments of 20 W · min−1, on a cycle ergometer. The AT was determined by the V-slope-method. Respiratory movements of the thorax, and the electrocardiogram were monitored. The instantaneous frequency of the HF component of HRV and of the respiratory signal were obtained by the Hilbert transformation. Both frequencies were closely related, the cross correlation coefficient being between 0.84 and 0.99. Various patterns of HRV and respiration were observed during the protocol. Remarkably, however, in over 90% of these cases, a shift in the instantaneous frequency of the HF component occurred during the transition from aerobic to anaerobic work. The difference between the AT determined by gas analysis and the AT evaluated as the power output (AT f ), calculated using the approximation of the curve of the instantaneous frequency of HF by hyperbolic tangent functions, varied between 2 and 14%. In conclusion, the present study demonstrates significant changes in the behavior of the instantaneous frequency of HF in the region of the AT.
    Type of Medium: Electronic Resource
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