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  • 1
    Electronic Resource
    Electronic Resource
    Structure of gap junctions in cultures of normal and neoplastic bladder epithelial cells (1981)
    Springer
    Cellular and molecular life sciences 37 (1981), S. 248-250 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Normal rat urinary bladder epithelial cells contain small subunit (PF-1) and large subunit (PF-2) gap junctions, whereas carcinoma cells only contain PF-1 gap junctions. The absence of PF-2 gap junctions, which are composed of larger connexons with slightly larger ionic channels, may contribute to altered metabolic coupling between urinary bladder carcinoma cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01991636
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The murine calcium-sensitive chloride channel (mCaCC) is widely expressed in secretory epithelia and in other select tissues (1998)
    Springer
    Histochemistry and cell biology 110 (1998), S. 43-49 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  The tissue and cellular expression pattern of a recently cloned murine calcium-sensitive chloride channel (mCaCC) was determined. In situ hybridization was performed on formalin-fixed, paraffin-embedded murine tissues using digoxigenin-labeled, single-stranded RNA probes. The data were substantiated with northern blot and reverse transcriptase–polymerase chain reaction analyses. All three assays consistently indicated strong expression in tissues with secretory or ion regulatory functions, such as mammary gland, respiratory and intestinal epithelia, gall bladder, pancreas, kidney, uterus, and epididymis. Additional mCaCC expression was observed in germinal centers of lymphatic tissues, in spermatids, and in keratinocytes of the skin, esophagus, and cornea. The results are in accordance with previous electrophysiological reports on calcium-activated chloride conductances in various murine exocrine secretory epithelia and suggest a role of mCaCC in transepithelial ion transport. However, expression in other than secretory tissues indicates a more complex function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004180050263
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Fluorescenzmikroskopische Untersuchungen der cerebralen Amyloidose bei alten Hunden und senilen Menschen (1971)
    Springer
    Acta neuropathologica 19 (1971), S. 121-128 
    Details
    ISSN: 1432-0533
    Keywords: Amyloidosis ; Brain ; Dog ; Man ; Fluorescence Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The brains of 44 dogs aged 12 to 17 years were studied for cerebral amyloidosis using thioflavine fluorescence and silver impregnation methods. The findings were compared with those in senile humans. Using the same technical methods, no qualitative differences can be found between comparable amyloid changes in dogs and man. The only important deviation is a quantitative difference of amyloidosis in the leptomeningeal and cortical vessels and in the cortical parenchyma. The vascular deposits show 3 types of lesions—finely flaky, segmental and tube-like. In aged dogs the vascular lesions structurally conform to congophilic angiopathy, while in man chiefly the “drusige Entartung” of cortical arteries and capillaries (Scholz) is found (late type of congophilic angiopathy). In addition to classical types of senile plaques, sponge-like, diffuse and pale plaques are distinguished. In dogs and man there is close morphological relationship between senile plaques and vascular amyloidosis. The similarity of morphological changes in brain of senile humans and aged dogs are emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688490
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  • 4
    Electronic Resource
    Electronic Resource
    Elektronenmikroskopische Untersuchungen der cerebralen Amyloidose bei alten Hunden und einem senilen Menschen (1971)
    Springer
    Acta neuropathologica 19 (1971), S. 129-136 
    Details
    ISSN: 1432-0533
    Keywords: Amyloidosis ; Brain ; Dog ; Man ; Electron Microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fluorescent changes in the brains of 4 aged dogs and one senile human were studied with the electron microscope using a special techique to reembed conventional histological sections in plastic (Rossiet al., 1970). Using this method typical amyloid filaments were found in fluorescent leptomeningeal and cortical vessels and in fluorescent plaques in the cerebral cortex. Leptomeningeal and cortical vessels in aged dogs and senile human disclosed dense intercellular accumulation of amyloid extending throughout the whole vessel wall. Contrary to man, perivascular penetration of amyloid filaments were not seen in the dog. They are, however, indicated by the presence of filaments in the adventitia. Senile plaques in both species are formed by the same elements. The central core of the plaque predominantly contains amyloid, while the periphery discloses various dystrophic changes of the ageing brain. Alzheimer filaments clearly distinguished from normal neurofilaments and from amyloid were present in the human brain but were absent in the dog brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688491
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  • 5
    Electronic Resource
    Electronic Resource
    Association of asymmetric unit membrane plaque formation in the urinary bladder of adult humans with therapeutic radiation (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 1645-1647 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Asymmetric unit membrane (AUM) is a component of the luminal membrane of urinary bladder in many species. In normal human adults it is inconspicuous, but it becomes prominent following incidental exposure to therapeutic irradiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01934049
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  • 6
    Electronic Resource
    Electronic Resource
    Magnesium deficiency in young Norway spruce (Picea abies [L.] Karst.) trees induced by NH4NO3 application (1997)
    Springer
    Plant and soil 195 (1997), S. 283-291 
    Details
    ISSN: 1573-5036
    Keywords: forest decline ; magnesium deficiency ; needle-tip yellowing ; nitrogen saturation ; nutrient imbalances ; soil acidification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Young Norway spruce trees were grown in 94 pots (2 per pot) on soil substrate derived from granite with low Mg saturation and were fertilized with different amounts of NH4NO3 (in total 25, 61, and 97 kmol N ha-1) over a period of four years, partly at an experimental station, partly at a high-elevation site in the Bavarian Forest. A fourth set of trees received 9.4 kmol Mg ha-1 in addition to 25 kmol N. Depending on the treatment, needle chlorosis developed in the course of the experiment. Improved light conditions after three years accelerated the yellowing process. The chlorotic Norway spruce trees showed a severe Mg deficiency and an imbalanced N:Mg ratio. The shoot length increment, the stem diameter, and the needle weights however were not influenced by the fertilization. Excessive applications of NH4NO3caused the substrate to become depleted of Mg. The successful experimental induction of the characteristic tip yellowing of older needles of Norway spruce growing on acidic soils at higher altitudes allowed hypotheses on the causes and processes of this type of forest decline to be tested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004291200514
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    Paper (German National Licenses)
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