ISSN:
0749-1581
Schlagwort(e):
Polyene macrolides
;
Amphotericin B
;
Solution-state conformation
;
2D NMR
;
COSY
;
ROESY
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
1H NMR data for amphotericin B methoxycarbonylmethylamide extracted from DQF-COSY, ROESY and 1D spectra were compared with x-ray data for amphotericin B. The conformation of amphotericin B in solution was identical with that found by x-ray analysis in the solid state. Most of the relay artifacts observed in the ROESY spectrum were recognized, and their pathways of formation were assigned.
Zusätzliches Material:
3 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/mrc.1260300402
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