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  • 1
    Electronic Resource
    Electronic Resource
    Replication terminus for DNA polymerase I during initiation of pAMβ1 replication: role of the plasmid-encoded resolution system (1997)
    Oxford BSL : Blackwell Science Ltd
    Molecular microbiology 23 (1997), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Replication of plasmid pAMβ1 is initiated by DNA polymerase I (Pol I) and completed by DNA polymerase III holoenzyme contained in the replisome machinery. In this study we report that initiation of DNA replication generates D-loop structures containing the nascent leading strand paired to its template, and that D-loop extension is arrested ≈230 bp from the initiation site of DNA synthesis in the presence of the plasmid-encoded resolvase. In vitro and in vivo data suggest that this arrest is caused by a collision between Pol I and the resolvase bound to its target. As the arrested D-loop replication intermediates carry a single-stranded primosome-assembly site, we hypothesize that the biological role of the replication arrest is to limit the region replicated by Pol I and to promote the replacement of Pol I by the replisome in order to initiate concerted synthesis of the leading and lagging strands.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.1997.d01-1874.x
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  • 2
    Electronic Resource
    Electronic Resource
    Stereoselective binding of D or L-α-amino acids by Cu(II) complexes of N-benzenesulfonyl-L-α-phenylalanine
    Amsterdam : Elsevier
    Journal of Inorganic and Nuclear Chemistry 42 (1980), S. 1665-1667 
    Details
    ISSN: 0022-1902
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0022-1902(80)80339-3
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  • 3
    Electronic Resource
    Electronic Resource
    Nickel catalysed electrosynthesis of anti-inflammatory agents. Part II — Monitoring of the electrolyses by HPLC analysis. Role of the catalyst (1988)
    Springer
    Journal of applied electrochemistry 18 (1988), S. 116-119 
    Details
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract A method of analysis has been developed by HPLC to monitor the progress of the electrosynthesis of aryl-2 propionic acids. This method elucidates the role of the nickel catalyst.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01016214
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  • 4
    Electronic Resource
    Electronic Resource
    Lifestyle Determinants of Bone Mineral: A Comparison Between Prepubertal Asian- and Caucasian-Canadian Boys and Girls (2000)
    Springer
    Calcified tissue international 66 (2000), S. 320-324 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Bone mineral — Calcium — Physical activity — Children — Ethnicity.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. The purpose of this study was to examine the difference in lifestyle and morphometric factors that affect bone mineral and the attainment of peak bone mass in 168 healthy Asian (n = 58) and Caucasian (n = 110) Canadian, prepubertal girls and boys (mean age 8.9 ± 0.7) living in close geographical proximity. DXA (Hologic 4500) scans of the proximal femur (with regions), lumbar spine, and total body (TB) were acquired. We report areal bone mineral densities (aBMD g/cm2) at all sites and estimated volumetric density (νBMD, g/cm3) at the femoral neck. Dietary calcium, physical activity, and maturity were estimated by questionnaire. Of these prepubertal children, all of the boys and 89% of the girls were Tanner stage 1. A 2 × 2 ANOVA demonstrated no difference between ethnicities for height, weight, body fat, or bone mineral free lean mass. Asian children consumed significantly less dietary calcium (35%) on average and were significantly less active (15%) than their Caucasian counterparts (P 〈 0.001). There were significant ethnicity main effects for femoral neck bone mineral content (BMC) and αBMD (both P 〈 0.001) and significant sex by ethnicity interactions (P 〈 0.01). The Asian boys had significantly lower femoral neck BMC (11%), aBMD (8%), and νBMD (4.4%). At the femoral neck, BMFL mass, sex, and physical activity explained 37% of the total variance in aBMD (P 〈 0.05). In summary, this study demonstrated differences in modifiable lifestyle factors and femoral neck bone mineral between Asian and Caucasian boys.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002230010067
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  • 5
    Electronic Resource
    Electronic Resource
    Synthesis of copper(II) complexes of asymmetric resins prepared by attachment of α-amino acids to crosslinked polystyrene (1977)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 21 (1977), S. 2589-2596 
    Details
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In order to use ligand exchange resins for chromatographic resolution of racemic compounds, two series of asymmetric sorbents were prepared by attachment of various optically active α-amino acids onto crosslinked polystyrene. Chloromethylated and chlorosulfonated styrene-divinylbenzene copolymers were prepared and then treated with α-amino acids. Results show that reaction of α-amino acids with polystyrene could be carried to a substitution of 15% to 40% of the aromatic rings depending on many parameters. Stable copper(II) complexes of the asymmetric resins were prepared. Potentiometric methods were adapted to the case of insoluble materials such as resins. These methods indicate that bis-chelate complexes are formed.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/app.1977.070211002
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