ISSN:
1432-1211
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract A B10.S(7R) anti-B10.S(9R) serum (anti-IJE k C d ) contained, as expected, antibodies specific for the I-E-subregion-encoded determinant Ia.7. However, tests on recombinant haplotypes demonstrated a series of unexpected weak extrareactions which could be interpreted to be directed against antigenic determinants encoded in the I-A subregion of the H-2 complex. The same type of extrareaction was observed in eluates from I-A s , I-E k cells coated with A.TH anti-A.TL (I-A s , I-E s anti-I-A k , I-E k ) serum. This reactivity in serum and eluates could be interpreted as cross-reactivity between products of the I-E and I-A subregions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00375504
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