ISSN:
1440-1681
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
1. In normolipidaemic young rats the intraperitoneal administration of diazepam (10 mg/kg) induced a marked fall of the total serum lipids and total cholesterol. A dose of 5 mg/kg brought about an increase of HDL2 lipoprotein fraction and an elevation of the HDL2/HDL2.HDL3 ratio.2. Margarine administration elicited a significant augmentation of the total serum lipids and a reduction of the HDL2/HDL2.HDL3 ratio. The intraperitoneal injection of diazepam in margarine-treated rats brought about a decrease of total serum lipids and total cholesterol, (when compared to the margarine values), an obvious elevation of the HDL2 fraction and of HDL2/HDL2.HDL3 ratio. The LDL, (β) fraction was decreased.3. These data confirm our earlier findings which show that diazepam improves the HDL cholesterol/total cholesterol ratio.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-1681.1985.tb00913.x
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