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  • 1
    Electronic Resource
    Electronic Resource
    A trial of the effect of nimodipine on outcome after head injury (1991)
    Springer
    Acta neurochirurgica 110 (1991), S. 97-105 
    Details
    ISSN: 0942-0940
    Keywords: Head injury ; outcome ; calcium antagonist ; nimodipine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We performed a randomised prospective double blind trial to study the effect of the calcium antagonist nimodipine on the outcome of head injured patients. The subjects were not obeying commands at the time of entry to the study, within 24 hours of injury. One hundred and seventy-five patients received nimodipine IV, 2 mg per hour for up to 7 days and 176 received placebo. The two groups were well matched for important prognostic features. Six months after injury 93 (53%) of the nimodipine group and 86 (49%) of the control group had a favourable outcome (moderate/good recovery). The relative increase in favourable outcomes (8%) was not significant but is compatible (95% C.I.) with an increase in favourable outcomes in treated patients by 33% or a decrease by 12%. Nimodipine was well tolerated and there were few adverse reactions; means of systolic and diastolic blood pressures and the intracranial pressure did not differ between the groups. It is unlikely that nimodipine has a marked effect on outcome (ie an increase in favourable outcome of 〉15%) after head injury of this severity but the study does not exclude a modest but clinically useful benefit.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01400674
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Radiologists and visual acuity (1997)
    Springer
    European radiology 7 (1997), S. 41-43 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Visual acuity ; Radiologists ; Monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Visual acuity (VA) and potential risks to the radiologist's eyesight have been relatively neglected subjects in the radiological literature. This study comprises two parts, the first consisting of a questionnaire on this subject sent to a random sample of 480 practising radiologists in the United Kingdom, and the second, a spot check of the VA of radiologists in our department. Of questionnaires, 73 %were returned. Of respondents, 76 % felt that ionising radiation could affect their vision, but only 13 % used lead glasses on a regular basis. A total of 71 % felt that regular monitoring of eyesight should be required. Of 25 tested radiologists, 5 had suboptimal VA and could benefit from further correction. The pertinent literature is reviewed, and a case for periodic eyesight testing is presented, including VA and grey-scale discrimination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050106
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    MRI in children receiving total parenteral nutrition (1996)
    Springer
    Neuroradiology 38 (1996), S. 680-683 
    Details
    ISSN: 1432-1920
    Keywords: Key words Parenteral nutrition ; Manganese ; Basal ganglia ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cranial MRI was obtained in 13 of a group of 57 children receiving long-term parenteral nutrition, who were being investigated for hypermanganasaemia. Increased signal intensity on T1-weighted images has been reported in adult patients on long-term parenteral nutrition and with encephalopathy following chronic manganese exposure in arc welding. It has been postulated that these changes are due to deposition of the paramagnetic trace element manganese. In excess manganese is hepato- and neurotoxic and we present the correlation of whole blood manganese levels with imaging findings. The age range of our patients was 6 months to 10 years, and the duration of therapy 3 months to 10 years. In 7 children we found characteristic increased signal intensity on T1-weighted images, with no abnormality on T2-weighted images. All patients had elevated whole blood manganese levels, suggesting that the basis for this abnormality is indeed deposition of manganese within the tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050333
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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