ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Starting from 1-(methylthiocarbonylmethyl)pyridinium iodide 1, several attemps were made to prepare 4,6-diaryl-2-pyridothiones. Synthesis of thioamides 2-10 was produced easily and with high yield, but thioamide behaves as a bad stabylising group. A modified method using a mixture of 1, compounds of the type R—NH2 and the corresponding chalcone, produced 2-pyridothiones only when R=H, and the compounds where isolated in the oxidised dithioform.Other reactions gave pyridinium salts, or 1,2-azoles, with no intervention of 1 in the process.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19863280214
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