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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 9 (1995), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim: To determine whether, in a susceptible opulation, dosing with 10 mg famotidine 1 h before an evening meal could decrease the interference with sleep caused by heartburn. Methods: Patients with a history of frequent heartburn (n= 309) were randomized to receive 10 mg famotidine or placebo 1 h before an evening meal likely to induce symptoms. Patients assessed the efficacy of the treatment in preventing heartburn after the meal, at bedtime and during the night. The number of awakenings due to heartburn and the consumption of antacid tablets taken to alleviate symptoms were also recorded. Results: Treatment groups were well matched and data from 302 patients were available for analysis. Compared to placebo, famotidine treated patients had: less heartburn after the meal (P 〈 0.0001 mean global scores), less interference with getting to sleep (P= 0.0156 mean global scores), fewer awakenings (P= 0.0001 difference in mean number) and better control of heartburn during the night (P 〈 0.0001 mean global scores). They were also almost three times less likely to need antacid treatment than the placebo group during the night (relative odds for no antacid 2.78 (95% CI: 1.29–5.96). Only four patients in each group suffered adverse events. Conclusion: Taking a 10 mg dose of famotidine 1 h before an evening meal appears to be a successful and well tolerated strategy for preventing post-prandial heartburn and avoiding the associated interference with sleep.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science
    Alimentary pharmacology & therapeutics 11 (1997), S. 0 
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim: To establish whether patients taking famotidine 10 mg to treat an episode of heartburn were protected from a recurrence of symptoms after a subsequent test meal. Methods: Frequent heartburn sufferers (n=366) were randomized to receive double blind treatment with famotidine 10 mg or 2×250 mg chewable alginate tablets within 30 min of a spontaneous episode of heartburn. After 4 h, patients with no or slight residual symptoms consumed a meal likely to induce heartburn. Over the next 4 h patients recorded the severity of heartburn and any consumption of ‘rescue’ antacids. At the end of this time they rated the global efficacy of their treatment in controlling meal-induced symptoms. Results: Study groups were well matched for all baseline characteristics. Of the 366 randomized patients, 276 took study medication and data from 269 patients (132 famotidine, 137 alginate) were analysed for efficacy. Compared to the alginate control group famotidine treated patients reported better global efficacy following the test meal (P〈0.001; relative odds for a more favourable response: 2.26 [95% CI: 1.45–3.53]). Fewer patients receiving famotidine resorted to antacid rescue (P = 0.038; relative odds for a more favourable response: 2.24 [95% CI: 1.04–4.79]) and peak heartburn was significantly less severe with famotidine treatment (P〈0.001; relative odds for a more favourable response: 2.90 [95% CI: 1.85–4.53]). Eleven famotidine-treated patients (8%) and 13 alginate patients (9%) reported adverse events. Conclusion: Compared to patients receiving an alginate preparation, patients self medicating with famotidine 10 mg for heartburn are better protected against a recurrence of their symptoms when they next eat. This suggests that the duration of acid control (9 h) previously demonstrated with this dose translates into a similar duration of measurable symptom control during the day.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 25 (1969), S. 884-885 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé L'effet d'une blessure naturelle sur le développement du tissu sclérifié et la distribution des feuilles est étudié sur laFagraea fragrans. Un méristème blessé est préparé et son histologie décrite. L'influence inhibitrice de la blessure et de l'hormone de blessure sur le développement du tissu sclérifié est très prononcée. Certains points importants de l'étude présente sont discutés, et comparés à des observations antérieures.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 197 (1963), S. 1125-1126 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Martens6'8 examined in detail the cuticle pattern on the floral parts of Tradescantia. In most instances he observed lamellate and striate cuticles and only in few cases the reticulate type. Scarcely any other report has been made about the occurrence of reticulate cuticle in plants. The present ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 20 (1964), S. 388-388 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Bien que le phénomène de Polyembryonie ait été signalé pour dix-neuf generes de plants de la famille des Orchidaceae, rien n'a été publié à ce sujet sur le genreVanda. Nous avons observé, dans les graines mûres d'uneVanda mixte aussi bien que dans celles germant sur de l'agar-agar, certains cas de Polyembryonie. Cet article rend compte du développement des embryons étudiés.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 24 (1968), S. 298-299 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Blätter vonFagraea fragrans enthalten polymorphe Sklereide Indolyl-Essigsäure (IES) in einer Konzentration von 0,125% hemmt die Verholzung der Sklereiden, höhere IES-Konzentrationen unterdrücken die Bildung der Sklereiden vollständig.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 44 (1988), S. 72-73 
    ISSN: 1420-9071
    Keywords: Agrobacterium tumefaciens ; nopaline plasmid ; tropical timber tree ; Fagraea fragrans ; genetic transformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Agrobacterium tumefaciens A208 with nopaline plasmid pTiT37 was used to obtain stem tumors on plantlets ofFagraea fragrans grown in vitro. Bacterial elimination and tissue proliferation were simultaneously achieved by growing tumors on cefatoxime medium. After some tissue growth the shoots regenerated. An examination of these showed the presence of nopaline, indicating genetic transformation by T-DNA.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Annali di matematica pura ed applicata 110 (1976), S. 211-222 
    ISSN: 1618-1891
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary The aim of the present paper is to study a nonlinear stochastic integral equation of the form $$x(t; \omega ) = h(t, x(t; \omega )) + \mathop \smallint \limits_0^t k_1 (t, \tau ; \omega )f_1 (\tau , x(\tau ; \omega ))d\tau + \mathop \smallint \limits_0^t k_2 (t, \tau ; \omega )f_2 (\tau , x(\tau ; \omega ))d\beta (\tau ; \omega )$$ . Sufficient conditions are given for the existence and uniqueness of a random solution, a second order stochastic process. Special cases of the above mixed Lebesgue-Ito-Doob type of integral equation are given which are useful in applications. In addition, an example of a stochastic control system illustrates the usefulness of the theoretical findings.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Annali di matematica pura ed applicata 89 (1971), S. 309-320 
    ISSN: 1618-1891
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary Sufficient conditions are given under which the solutions of the integral equation $$\sigma (t) = f(t,\sigma (t)) + \int\limits_0^t {G(t - u)\varphi (\sigma (u))} du$$ approach 0 as t → ∞. The condition imposed on the kernel is of the frequency type which admist a geometric interpretation.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Plant cell, tissue and organ culture 41 (1995), S. 193-196 
    ISSN: 1573-5044
    Keywords: Dipterocarpaceae ; tissue culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Plantlet development from in vitro cultures of Hopea odorato Roxb. is described. Embryos excised from seeds and cultured on Gamborg's B5 or modified Murashige and Skoog (MS) medium with benzyladenine (BA, 2.2–22.2 μM) produced axillary shoots at cotyledonary and/or stem nodes. Shoot production was greatest in germinated embryos on modified MS medium with 8.9 μM BA. Excised axillary shoots formed few buds when cultured on medium with BA and limited root development occurred on Woody Plant Medium with naphthaleneacetic acid. Nodal explants from aseptically grown plantlets sprouted axillary shoots in modified MS medium with BA.
    Type of Medium: Electronic Resource
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