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  • 1
    Electronic Resource
    Electronic Resource
    Peptide synthesis in cell-free extracts of Bacillus brevis 8185 (1968)
    s.l. : American Chemical Society
    Biochemistry 7 (1968), S. 3072-3077 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00849a007
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Role of Substance P in the Regulation of Ion Transport by CCKA and CCKB Receptors in Mouse Ileum (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 713 (1994), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1994.tb44113.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Inhibition of DNA Synthesis in Caco-2 Cells by Oxidative Stress (Amelioration by Epidermal Growth Factor) (1999)
    Springer
    Digestive diseases and sciences 44 (1999), S. 1902-1909 
    Details
    ISSN: 1573-2568
    Keywords: CELL PROLIFERATION ; SUPEROXIDE ; HYDROGEN PEROXIDE ; ANTIOXIDANTS ; INTESTINE ; EPITHELIUM
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of oxidative stress in the regulationof intestinal epithelial proliferation was examined byevaluating the effect of H2O2andxanthine oxidase + xanthine (XO + X) on[3H]thymidine incorporation into DNA in Caco-2 cells. DNAsynthesis was highest 4 and 5 days after seeding, whileit declined rapidly between 5 and 12 days. Pretreatmentfor 0.5-24 h with H2O2or XO + X reduced DNA synthesis on 4- to6-day-old, but not on 7- to 20-day-old cells. The effectof XO + X on DNA synthesis was significantly reduced bycatalase, superoxide dismutase, and ferric chloride, but pretreatment with deferoxamine potentiatedXO + X-induced inhibition of DNA synthesis.Coadministration of epidermal growth factor (EGF) for 24hr reduced the H2O2and XO +X-induced inhibition of DNA synthesis; this effect of EGFwas not observed up to 8 hr. Results show thatO2-and H2O2rapidlyinhibit DNA synthesis in Caco-2 cells and that EGFrestores DNA synthesis in oxidant-treatedcells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018815327769
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Salivary Epidermal Growth Factor Plays a Role in Protection of Ileal Mucosal Integrity (1997)
    Springer
    Digestive diseases and sciences 42 (1997), S. 2175-2181 
    Details
    ISSN: 1573-2568
    Keywords: PARACELLULAR PERMEABILITY ; MUCOSAL PROTECTION ; TIGHT JUNCTIONS ; SALIVA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of salivary epidermal growth factor(EGF) in the maintenance of ileal mucosal integrity wasstudied by evaluating the effects of sialoadenectomy onluminal EGF levels, ileal tissue resistance(Rt), and unidirectional flux of[51Cr]EDTA. Mice in groups 1 (SLX) and 2 (SLX+ EGF) were subjected to sialoadenectomy, while mice ingroups 3 (Sham) and 4 (Sham EGF) underwent a shamprocedure. All animals received normal diet and water, except that EGF(100 ng/ml) was added to water for SLX + EGF and Sham +EGF mice. At seven days after surgery, luminal EGFlevels in gastrointestinal segments and ileal R were significantly reduced by sialoadenectomy, whichwas prevented by EGF supplementation. Unidirectionalflux of [51Cr]EDTA was 6- to 22-fold greaterin the ileum of sialoadenectomized mice, which wasprevented by EGF administration. Results suggest thatsalivary EGF may be the major source of intestinal EGF,and it may play a role in maintenance of ileal mucosalintegrity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1018855525989
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  • 5
    Electronic Resource
    Electronic Resource
    Sterility in the rice hybrids and its significance (1962)
    Springer
    Euphytica 11 (1962), S. 137-142 
    Details
    ISSN: 1573-5060
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The degree of sterility resulting in F1 hybrids has been used by several workers while considering the relative affinity between the different varieties and sub-species within a species and that between different species. The authors contend that sterility cannot be used as a criterion and present spikelet sterility data in F1 hybrids of inter-varietal, inter-subspecific and interspecific crosses in the cultivated rices to support this contention. They conclude that the evolution of the three sub-species (viz., japonica, javanica and indica) may have taken place independent of each other from the various ecotypes of the putative species Oryza perennis through introgression although the possibility of the indica giving rise to japonica on the one hand and the javanica on the other cannot be altogether ruled out. The consequences of such a mode of evolution are discussed and the possibility of the existence of a slightly different set of linkage groups in indica rices compared with that of japonica rices is suggested.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00033785
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    Paper (German National Licenses)
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