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  • 1
    ISSN: 0014-5793
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0428
    Keywords: Obese-hyperglycaemic ; obesity ; genetic ; mice ; fatty acid synthesis ; 3H discrimination ; substrates ; lactate ; glucose ; ob/ob
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fatty acid synthesis was measured in vitro in pieces of adipose tissue from lean and obese-hyperglycaemic (ob/ob) mice, using 14C-glucose or 14C-lactate and 3H2O to obtain absolute rates of total fatty acid synthesis. In the presence of lipoproteintriglyceride (2.5 μmol/l) metabolic interaction occurred which decreased glucose incorporation into fatty acids by 30% in lean mouse tissue, but not in obese mouse tissue. In the absence of added insulin, the contribution of glucose to total fatty acid synthesis was 69% in obese mouse tissue, significantly lower than the value of 87% obtained in lean mouse tissue. Insulin increased the contribution of glucose to total synthesis in both lean and obese mouse tissues, although the value in obese mouse tissue (83%) remained lower than the value in lean mouse tissue (100%). Lactate was not a major precursor for fatty acid synthesis. When both lactate (2 mmol/l) and glucose (15 mmol/l) were present, the contribution of lactate to total fatty acid synthesis was not increased in obese mouse tissue, suggesting that even in the presence of insulin, about 30% of the carbon was provided by intracellular precursors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 345 (1977), S. 209-216 
    ISSN: 1435-2451
    Keywords: Vagotomy, proximal selective ; sophagus, diBection ; Vagomotor electrotest ; Vagotomie, proximal-selektive ; Oesophagus, Denudation des ; Vagotomischer Elektrotest
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: ZusammenfaBung Es wird eine standardisierte Technik der proximal-selektiven Vagotomie beschrieben, die sich in breiter klinischer Anwendung durch eine Vielzahl von Operateuren als zuverläBig und komplikationsarm erwiesen hat. Der Eingriff verläuft insechs Schritten: 1. Bestimmung der Antrum-Corpus-Grenze auf anatomischer Grundlage, 2. preliminärer, vagomotorischer Elektrotest, 3. Identifikation und Anschlingen der zu erhaltenden Nervenstrukturen, 4. Skelettieren der kleinen Kurvatur von distal nach proximal, 5. Freipräparieren der Cardia und Denudieren des intraabdominalen Oesophagus bis 6 cm proximal der Cardia, 6. Intraoperative Vollständigkeitskontrolle mit dem vagomotorischen Elektrotest. Grundsätzlich wird auf eine Drainageoperation verzichtet.
    Notes: Summary A standard technique of proximal selective vagotomy is described (PSV) that has proved reliable and safe in a broad multicenter clinical trial. We proceed in six steps: (1) determination of the antral-fundic boundary by anatomic criteria; (2) preliminary vagomotor electrotest; (3) identification of the nerve trunks and branches to be preserved; (4) diBection of the leBer curvature; (5) diBection of the cardia and of the intraabdominal esophagus up to 6 cm above the cardia; and (6) intraoperative aBeBment of completeneB by the vagomotor electrotest. PSV is usually carried out without a drainage procedure.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Hydroboration of Carbon Disulfide with Sodium Tetrahydridoborate. Pentasodium Tetrakis (dithiomethylene) borate, a Salt with a New “Tetrathioborate” AnionCarbon disulfide reacts in THF, acetonitrile, or N, N-dimethylthioformamide with NaBH4 to give pentasodium tetrakis(dithiomethylene) borate, 6. The reaction mechanism for the new anion [B⊖(S—CH2—S⊖)4] can be described by stepwise CS2 insertion to the B—H bonds of BH4⊖ and H⊖ transfer from BH4⊖ to the intermediates. The results of these reactions have been obtained by 1H and 11B NMR spectroscopy.
    Notes: Kohlenstoffdisulfid reagiert in THF, Acetonitril oder N,N-Dimethylthioformamid mit NaBH1 zu Pentanatrium-tetrakis(dithiomethylen)borat, 6. Die Bildung des neuen Anions [B⊖ (S—CH2—S⊖)4] erfolgt durch schrittweise CS2-Insertion in die B—H-Bindungen des BH4⊖-Ions sowie durch H⊖-Übertragung von BH4⊖ auf die Zwischenprodukte. Die 1H- und 11B-NMR-Spektren werden diskutiert.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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