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  • 1
    Electronic Resource
    Electronic Resource
    FatalSelenomonas sputigena septicemia probably originating from lung abscess (1985)
    Springer
    European journal of clinical microbiology & infectious diseases 4 (1985), S. 343-344 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of fatal septicemia withSelenomonas sputigena in an immunocompromised patient is reported. The patient had a lung abscess from which the septicemia is believed to have originated. In contrast to the only other case reported in the literature, the isolate from our patient was characterized by very slow and difficult growth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02013666
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  • 2
    Electronic Resource
    Electronic Resource
    Evaluation of two media for antibiotic susceptibility testing of anaerobic bacteria using the receiver operating characteristic procedure (1990)
    Springer
    European journal of clinical microbiology & infectious diseases 9 (1990), S. 667-671 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Wilkins-Chalgren agar and Meat-Yeast agar were evaluated as media for antibiotic susceptibility testing using 112 anaerobic bacterial strains. The results obtained with the two media using the diffusion method were compared with those obtained by the dilution method as reference method. The results were analyzed by the receiver operating characteristic (ROC) procedure allowing a graphic representation of sensitivity and specificity of the technique for each cut-off value. The area under the ROC curves was calculated to compare the accuracy of the two methods. Six antibiotics were tested including amoxicillin, cefoxitin, piperacillin, doxycycline and clindamycin. For amoxicillin and clindamycin, the two methods showed a high and identical discriminative power for distinguishing susceptible bacteria from the others. Diffusion in Wilkins-Chalgren agar appeared better than diffusion in Meat-Yeast agar for separating resistant bacteria from bacteria of intermediate susceptibility (amoxicillin p〈0.005; clindamycin p〈0.04). For other drugs, diffusion in Wilkins-Chalgren agar always had a discriminative power higher than that obtained with diffusion in Meat-Yeast agar for separating susceptible bacteria from the others (cefoxitin p〈0.0005; piperacillin p〈0.02; doxycycline p〈0.05). The Wilkins-Chalgren agar medium thus appeared superior to the Meat-Yeast agar medium using the ROC evaluation method, which would deserve wider utilization in the field of microbiology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01964269
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  • 3
    Electronic Resource
    Electronic Resource
    A penicillinase-producingFusobacterium nucleatum strain isolated from blood culture (1987)
    Springer
    European journal of clinical microbiology & infectious diseases 6 (1987), S. 695-696 
    Details
    ISSN: 1435-4373
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02013079
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Kinetics of bactericidal activity of antibiotics measured by luciferin-luciferase assay (1991)
    New York : Wiley-Blackwell
    Journal of Bioluminescence and Chemiluminescence 6 (1991), S. 193-201 
    Details
    ISSN: 0884-3996
    Keywords: Bioluminescence ; firefly luciferase ; antibiotics ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: ATP production, measured by the luciferin-luciferase assay, is an indicator of bacterial metabolic activity. This enzymatic assay yields rapid results (〈 5 minutes), permitting multiple measurements and establishment of ATP growth curves in order to study the kinetics of antibiotics in bacterial populations. The measurement of free or extracellular ATP, total ATP (extra and intracellular) and the ratio of free to total ATP are additional means of studying the bacteriostatic or bactericidal activity of antibiotics. An increase in free ATP is an indicator of extracellular movement due to alteration of the cell wall. The ratio free ATP/total ATP × 100 ≥ 50%, indicates bacteriallysis. These assays were used to study the effects of 14 antibiotics on two reference strains of Escherichia coli ATCC 25922 and Staphylococcus aureus 25923.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bio.1170060310
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    Paper (German National Licenses)
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