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  • 1
    Electronic Resource
    Electronic Resource
    Role of nuclear medicine in the treatment of malignant gliomas: the locoregional radioimmunotherapy approach (2000)
    Springer
    European journal of nuclear medicine 27 (2000), S. 601-609 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Malignant gliomas – Radioimmunotherapy – Monoclonal antibodies – Radioiodine – Radioyttrium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The high-grade malignant gliomas (anaplastic astrocytomas and glioblastoma) have a very bad prognosis since the available methods of treatment (surgery, radiotherapy and chemotherapy) are unable to control the progression of the disease for long. The use of specific monoclonal antibodies labelled with a suitable isotope (iodine-131 or yttrium-90) represents an effective approach to hamper tumour regrowth. Some authors have injected the antibodies intravenously, or have tried to increase the tumour/background ratio with the avidin/ biotin system. In many cases the labelled monoclonal antibodies were injected directly into the tumoral bed after the operation. The authors’ experiences concern a quite large locoregional radioimmunotherapy study which was performed by using antitenascin antibodies labelled initially with 131I and more recently with 90Y. The clinical results demonstrate the ability of this technique to control, for a long time, the growth of these tumours. The glioblastoma median survival was prolonged to 25 months (131I group) or 31 months (90Y group). The response rate (which comprises PR, CR and NED) was 47.1% (glioblastoma 131I group) or 40% ( glioblastoma 90Y group). In many cases a significant tumour shrinking effect was radiologically demonstrated. The use of 90Y proved more favourable in bulky lesions, and reduced the radioprotection problems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050549
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The use of herbicides for weed control in flooded rice in North Italy (1996)
    Springer
    Hydrobiologia 340 (1996), S. 265-269 
    Details
    ISSN: 1573-5117
    Keywords: flooded rice ; weed control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The use of chemicals to control weeds in flooded rice in the Po Valley, Italy is restricted by limited knowledge of potentially useful herbicides. Different strategies of chemical weed control, including different application timings of several types of herbicides are compared based on effectiveness and selectivity. Echinochloa spp., the most common weed was, in the experimental conditions, better controlled with early applications (pre-sowing and preemergence) of new herbicides which were effective substitutes for molinate, the use of which is no longer allowed in some Italian areas. Alisma plantago-aquatica, Bolboschoenus maritimus and Schoenoplectus macronatus were controlled by different types of herbicides applied post-emergence. Cinosulfuron (sulfonylurea) showed the highest effectiveness and selectivity in controlling the more common Hetherantera spp., even when applied in very low amounts.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00012766
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Assessment of the RSCL quality of life instrument during chemotherapy in an Italian setting (1996)
    Springer
    Quality of life research 5 (1996), S. 491-495 
    Details
    ISSN: 1573-2649
    Keywords: Advanced cancer patients ; chemotherapy ; quality of life ; Rotterdam Symptoms Checklist
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Evaluation of the quality of life of oncological patients is now perceived as a major element of cancer treatment, and various instruments for measuring it have been proposed. However, whatever instrument is used must be capable of reflecting the different ways in which different contexts and cultures respond to cancer. We administered the Italian version of the Rotterdam Symptom Checklist (RSCL) to 60 patients with advanced disease attending five oncological centres in Romagna (central Italy). The RSCL was found to be able to measure both psychological and physical well-being and to detect a difference between patients on low/medium and those on high-burden chemotherapy. The Italian version of the RSCL is an adequate scale that is capable of capturing patient perceptions and could be used for monitoring the quality of life of Italian patients participating in clinical trials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00540021
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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